Fibroblast Growth Factor Chimera (FGFC), recombinant

for Cellbiology

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

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Comparison	Product Number	Package Size	Price	Availability	Certificate of Analysis	Purchase
	Distributor 067-06591 Barcode No 4548995046949	100ug	List Price 788.00 USD	In stock in Japan	Certificate of Analysis	Distributor
	Distributor 063-06593 Barcode No 4548995046956	100ug x5	Inquire	Out of Stock Inquire	Certificate of Analysis	Distributor

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Overview / Applications

Outline	This product is for research use only. Do not administer it to human. This is a chimeric cytokine composed of acidic fibroblast growth factor (FGF-acidic) and basic fibroblast growth factor (FGF-basic). It is more structurally stable than FGF-acidic, and in the absence of heparin, promotes endothelial cell proliferation more strongly than FGF-acidic and FGF-basic. Further, it binds to all FGF receptor subtypes and FGF activity is exhibited. With respect to radiation exposure, FGF-acidic is more protective against radiation damage than is standard; however, as a chimera with FGF-basic in FGFC, in vivo stability and FGF signal-dependent cell proliferative activity are improved, and enhanced survival rate after radiation exposure has been confirmed in mice.

Outline

This product is for research use only. Do not administer it to human.

This is a chimeric cytokine composed of acidic fibroblast growth factor (FGF-acidic) and basic fibroblast growth factor (FGF-basic).
It is more structurally stable than FGF-acidic, and in the absence of heparin, promotes endothelial cell proliferation more strongly than FGF-acidic and FGF-basic. Further, it binds to all FGF receptor subtypes and FGF activity is exhibited.
With respect to radiation exposure, FGF-acidic is more protective against radiation damage than is standard; however, as a chimera with FGF-basic in FGFC, in vivo stability and FGF signal-dependent cell proliferative activity are improved, and enhanced survival rate after radiation exposure has been confirmed in mice.

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Appearance	White lyophilisate
Origin / Source	E. coli expressed chimera protein of human FGF-acidic and FGF-basic.

Manufacturer Information

Alias

FGF1/FGF2 Chimera
Chimera of acidic FGF and basic FGF
Chimera of FGF1 and FGF2
FGF Chimera
FGFC

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For research use or further manufacturing use only. Not for use in diagnostic procedures.

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