Fibroblast Growth Factor Chimera (FGFC), recombinant

for Cellbiology

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

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	Distributor 067-06591 Barcode No 4548995046949	100ug	List Price 788.00 USD	In stock in Japan	Certificate of Analysis
	Distributor 063-06593 Barcode No 4548995046956	100ug x5	Inquire	Out of Stock Inquire	Certificate of Analysis

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Outline	This product is for research use only. Do not administer it to human. This is a chimeric cytokine composed of acidic fibroblast growth factor (FGF-acidic) and basic fibroblast growth factor (FGF-basic). It is more structurally stable than FGF-acidic, and in the absence of heparin, promotes endothelial cell proliferation more strongly than FGF-acidic and FGF-basic. Further, it binds to all FGF receptor subtypes and FGF activity is exhibited. With respect to radiation exposure, FGF-acidic is more protective against radiation damage than is standard; however, as a chimera with FGF-basic in FGFC, in vivo stability and FGF signal-dependent cell proliferative activity are improved, and enhanced survival rate after radiation exposure has been confirmed in mice.

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This product is for research use only. Do not administer it to human.

This is a chimeric cytokine composed of acidic fibroblast growth factor (FGF-acidic) and basic fibroblast growth factor (FGF-basic).
It is more structurally stable than FGF-acidic, and in the absence of heparin, promotes endothelial cell proliferation more strongly than FGF-acidic and FGF-basic. Further, it binds to all FGF receptor subtypes and FGF activity is exhibited.
With respect to radiation exposure, FGF-acidic is more protective against radiation damage than is standard; however, as a chimera with FGF-basic in FGFC, in vivo stability and FGF signal-dependent cell proliferative activity are improved, and enhanced survival rate after radiation exposure has been confirmed in mice.

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Appearance	White lyophilisate
Origin / Source	E. coli expressed chimera protein of human FGF-acidic and FGF-basic.

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Alias

FGF1/FGF2 Chimera
Chimera of acidic FGF and basic FGF
Chimera of FGF1 and FGF2
FGF Chimera
FGFC

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For research use or further manufacturing use only. Not for use in diagnostic procedures.

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