Resistin, Human, recombinant

for Biochemistry

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

Molecular Weight :: 19500

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	Distributor 187-01801 Barcode No 4987481420199	25ug	List Price 461.00 USD	Out of Stock Inquire	Certificate of Analysis

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Outline	This product is for research use only. Do not administer it to human. [BIOCHEMISTRY] Diabetes Resistin is a dimeric hormone secreted by mast cells and is attracting attention as a substance which impairs insulin action. TNF-alpha and free fatty acid are known as resistins.Serum resistin concentration decreases with administration of antidiabetic drugs and is elevated when obesity occurs. It was also found that administration of resistin-neutralizing substance to obese mice restored serum glucose levels and insulin action. Based on these findings, it is believed that resistin is a key link between obesity and diabetes. [Reference] Steppan, C.M., et al.: Nature, 409, 307 (2001). Source: Human resistin cDNA expressed in E. coli Appearance: Sterile filtered and then lyophilized from 20mM Tris (pH 8.0) Endotoxin: max. 1.0 ng/ug (ug: microgram) Reconstitution: Reconstitute in water to a concentration of 0.1~1.0 mg/mL. The reconstituted resistin should be stored in working aliquots at -20 degrees C.

Outline

This product is for research use only. Do not administer it to human.

[BIOCHEMISTRY]

Diabetes

Resistin is a dimeric hormone secreted by mast cells and is attracting attention as a substance which impairs insulin action. TNF-alpha and free fatty acid are known as resistins.Serum resistin concentration decreases with administration of antidiabetic drugs and is elevated when obesity occurs. It was also found that administration of resistin-neutralizing substance to obese mice restored serum glucose levels and insulin action. Based on these findings, it is believed that resistin is a key link between obesity and diabetes.

[Reference]

Steppan, C.M., et al.: Nature, 409, 307 (2001).

Source: Human resistin cDNA expressed in E. coli
Appearance: Sterile filtered and then lyophilized from 20mM Tris (pH 8.0)
Endotoxin: max. 1.0 ng/ug (ug: microgram)
Reconstitution: Reconstitute in water to a concentration of 0.1~1.0 mg/mL. The reconstituted resistin should be stored in working aliquots at -20 degrees C.

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Origin / Source	E. coli expressed human resistin
Purity	Bacterial endotoxins : <0.1ng/ug

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