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Detail Information
  1. Top
  2. Cell Culture
  3. Stem Cell Culture
  4. Undifferentiated State Maintenance / Differentiation Induction
  5. Small Molecules for ES/iPS cells Research
  6. Y-27632 ( GMP-compliant )
  1. Top
  2. Cell Culture
  3. Stem Cell Culture
  4. Undifferentiated State Maintenance / Differentiation Induction
  5. Y-27632
  6. Y-27632 ( GMP-compliant )

Y-27632 ( GMP-compliant )

for Cell Culture
Specification Assay :
99.5+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep below 25 degrees C.
CAS RN® :
331752-47-7
Molecular Formula :
C14H21N3O・2HCl・H2O
Molecular Weight :
338.27
GHS :
Citations (1)
PubMed Central® search
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  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Availability
Certificate of Analysis
Purchase
Distributor
252-00701
Barcode No
4548995083791
5mg
List Price
825.00 USD

In stock in Japan
Distributor
Distributor
258-00703
Barcode No
4548995083807
25mg
List Price
3,300.00 USD

In stock in Japan
Distributor

※Check  availability  in the US with the distributor.

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Y-27632 Comparison Chart

ICH-Q7 ISO9001 Sterility
test		 Viable
count
test		 Animal-
derived-
free		 Bacterial
Endotoxin
test		 Mycoplasma
test		 Powder/
Liquid		 References*
Y-27632 (GMP-compliant)** ✓ ✓ - ✓ ✓ ✓ ✓ Powder -
Y-27632, MF*** - ✓ - ✓ ✓ ✓ ✓ Powder
CultureSure® Y-27632 - ✓ - - ✓ ✓ ✓ Powder
CultureSure® 10mmol/L
Y-27632 Solution,
Animal-derived-free 		- ✓ ✓ - ✓ ✓ ✓ Liquid
Sterilized with filter

* Click to move to the PubMed Central® search results.
** This product is complied with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.
*** The manufacturing process and analytical procedure are validated.

Overview / Applications

Outline It is a selective and potent inhibitor of ROCK (Rho-associated coiled-coil forming kinase/Rho binding kinase). Y-27632 has a variety of activities including vascular smooth muscle contraction through the ROCK signaling (Ki = 140 nmol/L p160ROCK). This product has been reported to suppress death of human ES/iPS cells at the time of cell dispersion and improves viability of the cells after cryopreservation.
This product complies with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.

Property

Appearance White - pale yellowish white, crystalline powder or powder
Specific Rotation +2.0 - +10.0 degrees (D/20 degrees C)
Purity Bacterial endotoxins : <0.25EU/mg

Manufacturer Information

Alias

  • ((R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide Dihydrochloride Monohydrate)

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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