Y-27632 ( GMP-compliant )
- for Cell Culture
- Specification Assay :
- 99.5+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep below 25 degrees C.
- CAS RN® :
- 331752-47-7
- Molecular Formula :
- C14H21N3O・2HCl・H2O
- Molecular Weight :
- 338.27
- GHS :
-
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- Structural Formula
- Label
- Packing
- SDS
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Comparison
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5mg
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In stock |
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25mg
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In stock in Japan |
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Document
Y-27632 Comparison Chart
| ICH-Q7 | ISO9001 | Sterility test |
Viable count test |
Animal- derived- free |
Bacterial Endotoxin test |
Mycoplasma test |
Powder/ Liquid |
References* | |
|---|---|---|---|---|---|---|---|---|---|
| Y-27632 (GMP-compliant)** | ✓ | ✓ | - | ✓ | ✓ | ✓ | ✓ | Powder | - |
| Y-27632, MF*** | - | ✓ | - | ✓ | ✓ | ✓ | ✓ | Powder | |
| CultureSure® Y-27632 | - | ✓ | - | - | ✓ | ✓ | ✓ | Powder | |
| CultureSure® 10mmol/L Y-27632 Solution, Animal-derived-free |
- | ✓ | ✓ | - | ✓ | ✓ | ✓ | Liquid Sterilized with filter |
* Click to move to the PubMed Central® search results.
** This product is complied with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.
*** The manufacturing process and analytical procedure are validated.
Overview / Applications
| Outline | It is a selective and potent inhibitor of ROCK (Rho-associated coiled-coil forming kinase/Rho binding kinase). Y-27632 has a variety of activities including vascular smooth muscle contraction through the ROCK signaling (Ki = 140 nmol/L p160ROCK). This product has been reported to suppress death of human ES/iPS cells at the time of cell dispersion and improves viability of the cells after cryopreservation. This product complies with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products. |
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Property
| Appearance | White - pale yellowish white, crystalline powder or powder |
|---|---|
| Specific Rotation | +2.0 - +10.0 degrees (D/20 degrees C) |
| Purity | Bacterial endotoxins : <0.25EU/mg |
Manufacturer Information
Alias
- ((R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide Dihydrochloride Monohydrate)
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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