A-83-01, MF
- for Cell Culture
- Specification Assay :
- 98.0+%(HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- CAS RN® :
- 909910-43-6
- Molecular Formula :
- C25H19N5S
- Molecular Weight :
- 421.52
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- Structural Formula
- Label
- Packing
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Comparison
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Certificate of Analysis
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5mg
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Out of Stock |
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25mg
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Out of Stock |
※Check availability in the US with the distributor.
Document
Application
Overview / Applications
| Outline | "This product is for research use only. Do not administer it to human.This is registered in Master File. A-83-01 is a selective inhibitor of TGF-β type I / activin receptor-like kinase (ALK5), type I activin / nodal receptor-like kinase (ALK4) / type I nodal receptor-like kinase (ALK7) . It inhibits phosphorylation of Smad2/3 and induced epithelial mesenchymal transition TGF-β. This product has little or no effect on osteogenic factor type I receptor, p38 MAP kinase and extracellular regulated kinase. In addition, it has been reported that rat iPS cells can be grown uniformly without differentiation and can be cultured for a long time by adding to rat's iPS cell culture medium. [Li, W., et al.: Cell Stem Cell, 4, 16(2009).] |
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| Precautions for Use | Packed on inactive gas |
Property
| Appearance | White - yellow, crystalline powder - powder or mass |
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| Solubility | Soluble in dimethylsulfoxide (2.5 mg/mL: All dissolved in water). Hardly soluble in water, ethanol and acetone. |
| Purity | Bacterial endotoxins : <0.01EU/mg |
Manufacturer Information
Alias
- 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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