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A-83-01, MF

for Cell Culture
Specification Assay :
98.0+%(HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
909910-43-6
Molecular Formula :
C25H19N5S
Molecular Weight :
421.52
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
010-26741
Barcode No
4548995057471
5mg
List Price
440.00 USD

Out of Stock

Distributor
018-26742
Barcode No
4548995057488
25mg
Inquire

Out of Stock

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline "This product is for research use only. Do not administer it to human.
This is registered in Master File.
A-83-01 is a selective inhibitor of TGF-β type I / activin receptor-like kinase (ALK5), type I activin / nodal receptor-like kinase (ALK4) / type I nodal receptor-like kinase (ALK7) . It inhibits phosphorylation of Smad2/3 and induced epithelial mesenchymal transition TGF-β. This product has little or no effect on osteogenic factor type I receptor, p38 MAP kinase and extracellular regulated kinase. In addition, it has been reported that rat iPS cells can be grown uniformly without differentiation and can be cultured for a long time by adding to rat's iPS cell culture medium.
[Li, W., et al.: Cell Stem Cell, 4, 16(2009).]
Precautions for Use Packed on inactive gas

Property

Appearance White - yellow, crystalline powder - powder or mass
Solubility Soluble in dimethylsulfoxide (2.5 mg/mL: All dissolved in water). Hardly soluble in water, ethanol and acetone.
Purity Bacterial endotoxins : <0.01EU/mg

Manufacturer Information

Alias

  • 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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