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KMI-429

for Cellbiology
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
753030-13-6
Molecular Formula :
C34H44N10O10
Molecular Weight :
752.77
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
115-00901
Barcode No
4987481613942
1mg
List Price
534.00 USD

Out of Stock

Document

SDS
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.

This product is a β-secretase inhibitor. Amyloid β produced in the body is drawing attention for its participation in the onset of Alzheimer's disease because senile plaques consisting mainly of amyloid β aggregates are observed extensively in the brain of patients with Alzheimer's disease. Among them, β-secretase (β-site APP cleaving enzyme; BACE) is drawing attention as a protease that cleaves amyloid β from amyloid β precursor protein (APP). IC50 = 3.9 nmol/L.

Property

Appearance White - pale brown, crystalline powder - powder

Manufacturer Information

Alias

  • 5-[[(2R,3S)-2-Hydroxy-3-[[3-[(2H-tetrazole-5-yl)carbonylamino]-L-Ala-L-Val-L-Leu-]amino]-4-phenybutyryl]amino]isophthalic acid
    L-Leucinamide, 3-[(2H-tetrazol-5-ylcarbonyl)amino]-L-alanyl-L-valyl-N-[(1S,2R)-3-[(3,5-dicarboxyphenyl)amino]-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]

For research use or further manufacturing use only. Not for use in diagnostic procedures.

Product content may differ from the actual image due to minor specification changes etc.

If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.

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