KMI-429
- for Cellbiology
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- CAS RN® :
- 753030-13-6
- Molecular Formula :
- C34H44N10O10
- Molecular Weight :
- 752.77
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- Structural Formula
- Label
- Packing
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1mg
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In stock in Japan |
※Check availability in the US with the distributor.
Document
Application
Overview / Applications
| Outline | This product is for research use only. Do not administer it to human. This product is a β-secretase inhibitor. Amyloid β produced in the body is drawing attention for its participation in the onset of Alzheimer's disease because senile plaques consisting mainly of amyloid β aggregates are observed extensively in the brain of patients with Alzheimer's disease. Among them, β-secretase (β-site APP cleaving enzyme; BACE) is drawing attention as a protease that cleaves amyloid β from amyloid β precursor protein (APP). IC50 = 3.9 nmol/L. |
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Property
| Appearance | White - pale brown, crystalline powder - powder |
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Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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