KT-430
- for Cellbiology
- Specification Assay :
- 95.0+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at RT.
- CAS RN® :
- 2133395-39-6
- Molecular Formula :
- C21H27N3O・3HCl
- Molecular Weight :
- 446.84
- Structural Formula
- Label
- Packing
- SDS
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Comparison
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10mg
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In stock in Japan |
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Document
Overview / Applications
| Outline | KT-430 is a low molecular compound derived from isoproterenol inhibits aggregation of tau protein. This compound shows 1) in vitro tau aggregation inhibitory activity (IC50 = 0.533uM) about 20 times of methylene blue, 2) blood-brain barrier permeability 3)reducing sarcosyl-insoluble tau in brain of P19 line mouse(Tau P301S) by oral administration(150mg/kg) |
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Property
| Appearance | White - slightly brown, crystals - powder |
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| Solubility | Water(10mg/mL) |
Manufacturer Information
Alias
- 2-(4-Phenylpiperazine-1-yl)-4-(1-piperidyl)phenol・3HCl
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