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KT-430

for Cellbiology
Specification Assay :
95.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at RT.
CAS RN® :
2133395-39-6
Molecular Formula :
C21H27N3O・3HCl
Molecular Weight :
446.84
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
119-01141
Barcode No
4548995083357
10mg
List Price
286.00 USD

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Overview / Applications

Outline KT-430 is a low molecular compound derived from isoproterenol inhibits aggregation of tau protein. This compound shows 1) in vitro tau aggregation inhibitory activity (IC50 = 0.533uM) about 20 times of methylene blue, 2) blood-brain barrier permeability 3)reducing sarcosyl-insoluble tau in brain of P19 line mouse(Tau P301S) by oral administration(150mg/kg)

Property

Appearance White - slightly brown, crystals - powder
Solubility Water(10mg/mL)

Manufacturer Information

Alias

  • 2-(4-Phenylpiperazine-1-yl)-4-(1-piperidyl)phenol・3HCl

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