MDC(CCL22), Human, recombinant

for Biochemistry

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at -20 degrees C.

Molecular Weight :: 8kDa

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	Distributor 133-13231 Barcode No 4987481381575	20ug	List Price JPY 45,000	In stock in Japan	Certificate of Analysis

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Product Specification Sheet

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20ug

Calibration Certificate

Application

Overview / Applications

Outline	While chemokines belonging to the "C-C" subfamily have been reported as potent chemotactic factors to monocytes in general, a group that shows chemotactic behavior to lymphocytes has recently been identified. In spite of being CC chemokines, they act specifically on lymphocytes not showing any activity on monocytes. These chemokines are called "immune chemokines" as opposed to general "inflammatory chemokines". MDC is expressed primarily in the thymus, and actT cells are the targets of MDC. Its receptor is CCR4.

Outline

While chemokines belonging to the "C-C" subfamily have been reported as potent chemotactic factors to monocytes in general, a group that shows chemotactic behavior to lymphocytes has recently been identified. In spite of being CC chemokines, they act specifically on lymphocytes not showing any activity on monocytes. These chemokines are called "immune chemokines" as opposed to general "inflammatory chemokines". MDC is expressed primarily in the thymus, and actT cells are the targets of MDC. Its receptor is CCR4.

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Origin / Source	E.coli expressed human MDC
Purity	Bacterial endotoxins: <0.1ng/ug

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MACROPHAGE-DRIVED CHEMOKINE,HUMAN,RECOMBINANT

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