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Endotoxin Measurement SystemToxinometer® ET-7000

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* The manufacturer or model name of the personal computer included in the system may be subject to change.
  • Supports "the Bacterial Endotoxin Test" in the United States / European / Japanese Pharmacopoeias.
  • For use in Kinetic-Turbidimetric, Kinetic-Chromogenic, and Gel-Clot assays.
  • Can be controlled and analyzed with the dedicated software "Toximaster® QC" form Windows® PC.
  • Conforms to the international certification standards for C-UL (CSA) and CE.
  • Systems comply with the FDA21 CFR Part 11 are also available.

Videos

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Product Profile

The Toxinometer® ET-7000 is a computer-operated kinetic incubating tube reader, which is exceptionally user-friendly and easily expandable. Depending on the number of samples to be processed, our state of the art expansion modules can be connected to allow for endotoxin testing in a wide range of fields and sample quantities. The temperature setting can be switched between 30 and 37 ℃, facilitating (1 → 3)-β-D-glucan and peptidoglycan test for research projects.

Features

  • A single assay module can simultaneously measure up to 16 samples
  • Up to 8 measurement modules can be connected to the unit to enable simultaneous measurement of 128 samples.
  • The Toxinometer® can test using both multi test and single test reagents

Main Specification

  • Light source : High intensity blue LED (Central wavelength: 430 nm)
  • Temperature control : 30/37 ℃(Set using the software)
  • Measurement time : Max. 200 min

Toxinometer® Measurement Principle

Light from an LED goes through the reaction tube filled with reaction mixture via aperture diaphragm 1.

The light passes through the reaction mixture and then, while coming through aperture diaphragm 2, is detected by the silicon photocell.

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Toxinometer® translates the reaction of the LAL reagent with endotoxin into changes in the light intensity transmitted at 430 nm. The light intensity remains constant for a while after the start of reaction, but gradually decreases as the reaction proceeds, and stops upon completion of the reaction.

The ratio of the light intensity l(t) to the light intensity at an early stage of reaction lo is defined as R(t), and the threshold R(th) of R(t) is determined. Based on this, Toxinometer® reads the period from the start of the reaction to the point at which R(t) reaches R(th) as the gelation time Tg or the activation time Ta.

R(t) = [l(t)/lo] x 100 %

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Quantification

A correlation between the endotoxin concentration and gelation time (Tg) is obtained, and the endotoxin concentration is calculated using the gelation time of a sample.

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Toximaster®

Exclusive software for efficient routine work & high quality analysis.

Protocol Settings

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Easy to ! Once you create a protocol, you can start a measurement immediately.

Time Course Graph

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Enables visual confirmation of measurement status.You can predict results and prepare the next steps.

Standard Curve

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Conveniently monitored!All information can be seen on one screen.

Part 11 Function

Electronic Signature

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All measurement records are linked to signatures.Never allows manipulation and falsification.

Audit Trail

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Major procedures are recorded automatically.History of operation can be confirmed as a log file.

Operation Authorities

Each account belongs to a specific group and each group can define its own authorities for operation.

  • Modify System Preferences
  • Load Protocol into Test Record
  • Register Instrument
  • Star Measurement
  • Register Protocol
  • Load Test Record
  • Register Reagent
  • Review Test Plan
  • Register Accessory
  • Confirm Test Record
  • Register standard Curve Data
  • Approve Test Record
  • Register Product
  • Submit Test Record

Etc ..

ANALYSIS SYSTEM
Catalog No. Product Name Contents
293-36061 Toxinometer® ET-7000
  • 1 Toxinometer® ET-7000
SOFTWARE Part11
Catalog No. Product Name Contents
299-36161 Toximaster® QC8 Part11 PC Set
  • 1 Personal computer
  • Toximaster® QC8Part11 Software
  • System Validation Doc.
SOFTWARE Non-Part11
Catalog No. Product Name Contents
296-36171 Toximaster® QC7 Non-Part11 PC Set
  • 1 Personal computer
  • Toximaster® QC7 Non-Part11 Software
Accessorie
Catalog No. Product Name
292-36271 Toxinometer® ET-7000 240V power cord

Topics

  • LAL Basic Knowledge
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Contact

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CONTACT