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Life Science

Life Science

Future of BDNF research

This article was written by Dr. Hisatsugu Koshimizu, Research Promotion Headquarters, Fujita Health University.

This series of articles has outlined the role of brain-derived neurotrophic factor (BDNF) in the normal development and function of the central nervous system (CNS) and its possible involvement in the...

Life Science

Another face of BDNF

This article was written by Naoki Adachi, Department of Physiology, School of Medicine, Showa University.

BDNF/TrkB signaling pathways play beneficial functions in the normal development of neural circuits and regulation of neurotransmission. Therefore, disruption of BDNF/TrkB signaling is a cause of dise...

Life Science

Regulation of Plasticity through the BDNF Pathway and its Role in Psychiatric Disorders

This article was written by Juzoh Umemori, PhD, Docent, A.I. Virtanen Institute, University of Eastern Finland.

The Brain-derived neurotrophic factor (BDNF) regulates neural plasticity, such as neuronal survival and differentiation, by acting on its receptor Neurotrophic receptor tyrosine kinase 2 (Ntrk2, TrkB)...

Life Science

Role of BDNF during development and its relation to neurodevelopmental disorders

This article was written by Dr. Shingo Suzuki, Department of Anatomy and Neurobiology, Faculty of Medicine, Kagawa University.

Brain-derived neurotrophic factor (BDNF) is a trophic factor released mainly from neurons in a neural activity-dependent manner. It is involved in memory and learning by inducing synaptic organization...

Life Science

BDNF Overview

This article was written by Dr. Nobuyuki Takei, Department of Brain Tumor Biology, Brain Research Institute, Niigata University.

Research on brain-derived neurotrophic factor (BDNF) has evolved from its "classical" actions of promoting neuronal survival and differentiation to rather novel actions of regulating neurotransmission...

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