Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by upper motor neuron degeneration in the motor area of the cerebral cortex as well as lower motor neuron d...

Parkinson's disease (PD) is pathologically characterized by dopaminergic neuronal loss in the substantia nigra pars compacta and formation of neuronal inclusion called Lewy body. The significance of t...

Parkinson's disease (PD) is a neurodegenerative disease clinically characterized by Parkinson symptoms and pathologically characterized by Lewy bodies and dopaminergic neuronal death.

Alzheimer's disease (AD) is neuropathologically characterized by the deposition of protein aggregates and progressive neuronal death in the brain. Pathological protein fibrils deposited in the brain o...

A senile plaque, one of characteristic brain pathological features of Alzheimer's disease (AD), is the brain parenchymal accumulation of abnormally aggregating insoluble proteins forming amyloid fibri...