Wako Blog

We introduce a wide range of topics of research, technical reports, tips on experiments and so on.

Life Science

2nd review: Role of BDNF during development and its relation to neurodevelopmental disorders

This article was written by Dr. Shingo Suzuki, Department of Anatomy and Neurobiology, Faculty of Medicine, Kagawa University.

Brain-derived neurotrophic factor (BDNF) is a trophic factor released mainly from neurons in a neural activity-dependent manner. It is involved in memory and learning by inducing synaptic organization...

Life Science

1st review: BDNF Overview

This article was written by Dr. Nobuyuki Takei, Department of Brain Tumor Biology, Brain Research Institute, Niigata University.

Research on brain-derived neurotrophic factor (BDNF) has evolved from its "classical" actions of promoting neuronal survival and differentiation to rather novel actions of regulating neurotransmission...

Analytical Chemistry Technical Report

[Chromatography Q & A]: What Methods are Available for LC/MS Analysis of Highly Polarized Analytes?

This article was written for No. 42 (October 2006), of Analytical Circle.

For columns used in LC/MS, highly versatile reverse-phase octadecyl-silica gel (C18, ODS) is a mainstay packing agent. This ODS packing agent, however, has difficulty in separating a particular type o...

Analytical Chemistry Technical Report

[Technical Report] Analysis of Veterinary Drugs, Tiamulin and Robenidine, Using Wakopak® Wakosil-II 5SIL-AQ

This article was written by Ms. Kimiko Yoshida, FUJIFILM Wako Pure Chemical Corporation, for Vol. 74 No. 3 (July 2006), of Wako Junyaku Jiho.
The content of this article is from the time of publication. It is not the latest information due to new knowledge and changes in regulatory rules after original publication.

Widespread proliferation of liquid chromatography-mass spectrometry (LC/MS) analysis has made LC/MS-compatible solvents, reagents, and analytical columns commercially available. For the analytical col...

Analytical Chemistry

[Chromatography Q & A]: Change into Simple Analytical Condition Using Smaller Volume of Solvent; Change of Column Size from 4.6 mmφ to 3.0 mmφ

This article was written for No. 52 (March 2009), of Analytical Circle.

When the column size is changed from 4.6 to 3.0 mm in internal diameter (I.D.), and the flow rate is reduced by half, the solvent volume can be reduced. Although analysis time is not reduced, such cha...

Analytical Chemistry Technical Report

[Chromatography Q & A]: Connection Types of HPLC Column Wakopak®

This article was written for No. 71 (December 2013), of Analytical Circle

In the past, manufacturers of HPLC systems applied different specifications to connectors. In HPLC systems using stainless-steel pipes and connectors, the first column determined specifications of the...

Analytical Chemistry Technical Report

[Technical Report] Characteristics of C30 HPLC Column Wakopak Navi C30-5

This article was written by Mamoru Kubota, FUJIFILM Wako Pure Chemical Corporation, for Vol. 69, No. 3 (July 2001) of Wako Junyaku Jiho. The content of this article is from the time of publication. It is not the latest information due to new knowledge and changes in regulatory rules after original publication.

While, as a reverse-phase HPLC column packing, C18(ODS) modified silica gel with a broad range of applicability and excellent durability is still the focus of interest, silica gel bonding alkyl groups...

Analytical Chemistry

Introduction of General-purpose Solvents by Specification

Do you know that solvents like ethanol and acetone, which you often use, actually have more than 50 specification? In this article, we outline the specifications of reagents including general-purpose ...

Analytical Chemistry Technical Report

[Technical Report] Development of α-Glucosidase Inhibitory Activity Assay Kit

This article was written by Yasuko Matsui, FUJIFILM Wako Pure Chemical Corporation, for Vol. 85, No. 1 (January 2017) of Wako Junyaku Jiho.
The content of this article is from the time of publication. It is not the latest information due to new knowledge and changes in regulatory rules after original publication.

α-Glucosidase Inhibitory Activity Assay Kit (hereinafter referred to as "KIT") containing α-glucosidase enzyme with its enzyme activity being assured was developed. Combining with separately sold LabA...

[Technical Report] Quantitation of Amino Acids in Beverages Containing Some Amino Acids Using Wakopak® Ultra APDS TAG®

This article was written by Yuki Suto, FUJIFILM Wako Pure Chemical Corporation, for Vol. 85, No. 4 (October 2017) of Wako Junyaku Jiho.
The content of this article is from the time of publication. It is not the latest information due to new knowledge and changes in regulatory rules after original publication.

Since asparagine was discovered by isolating from the juice of asparagus in 1806, amino acids have been essential in our lives for the functions which are roughly classified into 4 categories: use as ...

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