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Y-27632 ( GMP-compliant )

for Cell Culture
Specification Assay :
99.5+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep below 25 degrees C.
CAS RN® :
331752-47-7
Molecular Formula :
C14H21N3O・2HCl・H2O
Molecular Weight :
338.27
GHS :
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
252-00701
Barcode No
4548995083791
5mg
List Price
JPY 120,000

In stock in Japan

Distributor
258-00703
Barcode No
4548995083807
25mg
List Price
JPY 480,000

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Y-27632 Comparison Chart

ICH-Q7 ISO9001 Sterility
test
Viable
count
test
Animal-
derived-
free
Bacterial
Endotoxin
test
Mycoplasma
test
Powder/
Liquid
References*
Y-27632 (GMP-compliant)** - Powder -
Y-27632, MF*** - - Powder
CultureSure® Y-27632 - - - Powder
CultureSure® 10mmol/L
Y-27632 Solution,
Animal-derived-free
- - Liquid
Sterilized with filter

* Click to move to the PubMed Central® search results.
** This product is complied with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.
*** The manufacturing process and analytical procedure are validated.

Overview / Applications

Outline It is a selective and potent inhibitor of ROCK (Rho-associated coiled-coil forming kinase/Rho binding kinase). Y-27632 has a variety of activities including vascular smooth muscle contraction through the ROCK signaling (Ki = 140 nmol/L p160ROCK). This product has been reported to suppress death of human ES/iPS cells at the time of cell dispersion and improves viability of the cells after cryopreservation.
This product complies with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.

Property

Appearance White - pale yellowish white, crystalline powder or powder
Specific Rotation +2.0 - +10.0 degrees (D/20 degrees C)
Purity Bacterial endotoxins : <0.25EU/mg

Manufacturer Information

Alias

  • ((R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide Dihydrochloride Monohydrate)

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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