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CultureSure® A-83-01

for Cell Culture
Specification Assay :
98.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
909910-43-6
Molecular Formula :
C25H19N5S
Molecular Weight :
421.52
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
039-24111
Barcode No
4548995036209
2mg
List Price
JPY 17,600

In stock in Japan

Distributor
035-24113
Barcode No
4548995036216
10mg
List Price
JPY 59,400

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.
This is a selective inhibitor of TGF-β type II/activin receptor-like kinase (ALK5), type I activin/nodal receptor-like kinase (ALK4), and type I nodal receptor-like kinase (ALK7).
It inhibits Smad2/3 phosphorylation, and inhibits TGF-β induced epithelial to mesenchymal transformation.
It exerts almost no effect on bone morphogenetic protein type I receptor, p38 MAP kinase, and extracellular signal-regulated kinase. Furthermore, it has been reported that when added to rat iPS cell culture medium, it facilitates uniform growth of rat iPS cells without differentiation, and can be cultivated over a long period.
[Li, W. Cell, 4, 16 (2009).]
Precautions for Use Packed on inactive gas

Property

Appearance White - yellow, crystalline powder - powder or mass
Purity Bacterial endotoxins : <0.01EU/mg

Manufacturer Information

Alias

  • 1H-Pyrazole-1-carbothioamide, 3-(6-methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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