Analytical Chemistry

Risk Assessment and Control in the Guideline for Elemental Impurities in Drugs

The original article by Rina Nishioka, Soichiro Hanakawa of the Sumika Chemical Analysis Service, Ltd., appeared in an e-newsletter of FUJIFILM Wako Pure Chemical Corporation and was translated by the company.

A regulatory guideline for elemental impurities in drug products was formulated by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH). In Jap...

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Analytical Chemistry

Effects of Trace Metals (Impurities) in Chemicals Used in Semiconductor Manufacture and Their Analysis

The original article by Yukihisa Kawada of the FUJIFILM Corporation, appeared in an e-newsletter of FUJIFILM Wako Pure Chemical Corporation and was translated by the company.

In recent years, the manufacturing process for semiconductors has become increasingly complex in order to meet the technical requirements for smaller size and higher performance. In this situation, qu...

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Analytical Chemistry

Arsenic compounds contained in various foods

Arsenic (As) is an element occurring in the Earth's crust mainly as sulfides such as As3S3, As4S4, and FeAsS. Because it is released into the environment through natural phenomena such as volcanic act...

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Life Science

Future of BDNF research

This article was written by Dr. Hisatsugu Koshimizu, Research Promotion Headquarters, Fujita Health University.

This series of articles has outlined the role of brain-derived neurotrophic factor (BDNF) in the normal development and function of the central nervous system (CNS) and its possible involvement in the...

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Analytical Chemistry

Precautions in Pre-treatment of Environmental Water Samples by Chelating Resin Preconcentration Method

The original article by Dr. Eiji Fujimori of the National Environmental Research and Training Institute, Ministry of the Environment, appeared in an e-newsletter of FUJIFILM Wako and was translated by the company.

Inductively coupled plasma mass spectrometry (ICP-MS) is capable of simultaneous analysis of multiple elements at extremely low levels and is the most sensitive elemental analysis method among common ...

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Life Science

Another face of BDNF

This article was written by Naoki Adachi, Department of Physiology, School of Medicine, Showa University.

BDNF/TrkB signaling pathways play beneficial functions in the normal development of neural circuits and regulation of neurotransmission. Therefore, disruption of BDNF/TrkB signaling is a cause of dise...

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Life Science

Regulation of Plasticity through the BDNF Pathway and its Role in Psychiatric Disorders

This article was written by Juzoh Umemori, PhD, Docent, A.I. Virtanen Institute, University of Eastern Finland.

The Brain-derived neurotrophic factor (BDNF) regulates neural plasticity, such as neuronal survival and differentiation, by acting on its receptor Neurotrophic receptor tyrosine kinase 2 (Ntrk2, TrkB)...

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Life Science

Role of BDNF during development and its relation to neurodevelopmental disorders

This article was written by Dr. Shingo Suzuki, Department of Anatomy and Neurobiology, Faculty of Medicine, Kagawa University.

Brain-derived neurotrophic factor (BDNF) is a trophic factor released mainly from neurons in a neural activity-dependent manner. It is involved in memory and learning by inducing synaptic organization...

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Life Science

BDNF Overview

This article was written by Dr. Nobuyuki Takei, Department of Brain Tumor Biology, Brain Research Institute, Niigata University.

Research on brain-derived neurotrophic factor (BDNF) has evolved from its "classical" actions of promoting neuronal survival and differentiation to rather novel actions of regulating neurotransmission...

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Analytical Chemistry Technical Report

[Chromatography Q & A]: Connection Types of HPLC Column Wakopak^®

This article was written for No. 71 (December 2013), of Analytical Circle

In the past, manufacturers of HPLC systems applied different specifications to connectors. In HPLC systems using stainless-steel pipes and connectors, the first column determined specifications of the...

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• chromatography