Wako Blog

We will introduce a wide range of topics of research, technical reports, tips on experiments and so on.

Life Science

Cell Culture Life Science

Novel Tool Box for EVs Therapy in Regenerative Medicine

MSC-derived extracellular vesicles isolated by PS affinity method have high anti-inflammatory and anti-fibrotic effects. Extracellular vesicles (EVs) are small and lipid bilayer particles released by...

Cell Culture Life Science

Co-culture studies to decode 'biological PINs' and exosomes

Recently, it has become evident that extracellular vesicles, including exosomes, play a major role in the communication of various cells in biology. As such, there has been a dramatic increase in the ...

Life Science

Why are exosomes getting a lot of attention?

First described over 30 years ago, exosomes are now being explored with great interest, particularly regarding their involvement in various diseases and in the development of targeted therapies. Exoso...

Life Science

Proteome analysis of exosomes

This article was written by Koji Ueda Project for Personalized Cancer Medicine, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Japan.

Exosomes are secretory microvesicles derived from intracellular vesicle trafficking pathways, which are involved in the extracellular release of unwanted molecules or delivery of molecules to distant ...

Life Science

Protein phosphorylation analysis using Phos-tag-based techniques

This article was written by Emiko Kinoshita-Kikuta, Eiji Kinoshita, Tohru Koike Department of Functional Molecular Science, Institute of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Hiroshima, Japan.

Proteins responsible for vital cellular functions use kinase-induced phosphorylation and phosphatase-induced dephosphorylation for their activation and deactivation, respectively. Wide varieties of di...

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