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Detail Information
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  4. Active Pharmaceutical Ingredients (APIs)
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  6. (R)-(-)-Phenylephrine Hydrochloride
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  2. Analytical Chemistry
  3. Food Nutrition / Functional Ingredients Analysis
  4. Alkaloids
  5. (R)-(-)-Phenylephrine Hydrochloride

(R)-(-)-Phenylephrine Hydrochloride

for Biochemistry
Specification Assay :
98.0+% (Titration)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at RT.
CAS RN® :
61-76-7
Molecular Formula :
C9H13NO2・HCl
Molecular Weight :
203.67
GHS :
Citations (1)
PubMed Central® search
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SDS
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Price
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Certificate of Analysis
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Distributor
163-11791
Barcode No
4987481314689
5G
List Price
31.00 USD

In stock in Japan
Distributor

※Check  availability  in the US with the distributor.

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline A drug with exciting action on the effector organs of postganglionic sympathetic fibers is referred to as a sympathetic neuron exciting substance or an adrenergic substance. Sympathetic innervation organs have 2 types of receptors, alpha and beta, which are classified into the subtypes alpha-1, alpha-2 and beta-1, beta-2.Alpha-1 receptorAction substance; Adrenalin > noradrenaline > isoproterenol.Phenylephrine, methoxamineEffect: Bronchoconstriction, vasoconstriction, constriction of uterine muscle, bowel relaxation, stimulation of glycolysis, acceleration of lipolysisAlpha-2 receptorAction substance; Noradrenaline = adrenaline > isoproterenol.ClonidineEffect: Inhibition of noradrenaline release from sympathetic nerve ending, inhibition of glycolysis, inhibition of lipolysis, platelet aggregation, inhibition of renin secretionBeta-1 receptorAction substance; Isoproterenol > noradrenaline = adrenaline.DobutamineEffect: Increased heart rate, increased cardiac contractile force, acceleration of lipolysisBeta-2 receptorAction substance; Isoproterenol > adrenalin >> noradrenaline.Metaproterenol, salbutamolEffect: Bronchodilatation, vasodilation, uterus muscle relaxation, bowel relaxation, stimulation of glycolysis, tremorAdrenergic substance (alpha-1 receptor agonist). Strong and persistent hypertensive action due to peripheral vasoconstriction (increase in blood pressure is about one fifth of epinephrine), pupillary dilation.
An agent that stimulates the adrenoreceptor (alpha1) present in the sympathetic nervous system and causes hypertension, and is used to study the effect of a hypotensive drug and the distribution of adrenoreceptors.

Property

Appearance White, crystals - crystalline powder
pH pH (10g/L, 25 degrees C) : 4.5 - 5.5
Melting Point 140 - 145 degrees C
Specific Rotation [α]D20 -42.0 - -47.5° (c=10, H2O)

Manufacturer Information

Alias

  • (R)-(-)-PHENYLEPHRINE.HCL
    L-PHENYLEPHINE.HCL

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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