(R)-(-)-Phenylephrine Hydrochloride

for Biochemistry

Specification Assay :: 98.0+% (Titration)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at RT.

CAS RN^® :: 61-76-7
Molecular Formula :: C9H13NO2・HCl
Molecular Weight :: 203.67

GHS :

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SDS

Comparison	Product Number	Package Size	Price	Inventory
	Distributor 163-11791 Barcode No 4987481314689	5g	List Price 31.00 USD	In stock in Japan	Certificate of Analysis

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SDS

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Spectral Data

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Application

Overview / Applications

Outline	A drug with exciting action on the effector organs of postganglionic sympathetic fibers is referred to as a sympathetic neuron exciting substance or an adrenergic substance. Sympathetic innervation organs have 2 types of receptors, alpha and beta, which are classified into the subtypes alpha-1, alpha-2 and beta-1, beta-2.Alpha-1 receptorAction substance; Adrenalin > noradrenaline > isoproterenol.Phenylephrine, methoxamineEffect: Bronchoconstriction, vasoconstriction, constriction of uterine muscle, bowel relaxation, stimulation of glycolysis, acceleration of lipolysisAlpha-2 receptorAction substance; Noradrenaline = adrenaline > isoproterenol.ClonidineEffect: Inhibition of noradrenaline release from sympathetic nerve ending, inhibition of glycolysis, inhibition of lipolysis, platelet aggregation, inhibition of renin secretionBeta-1 receptorAction substance; Isoproterenol > noradrenaline = adrenaline.DobutamineEffect: Increased heart rate, increased cardiac contractile force, acceleration of lipolysisBeta-2 receptorAction substance; Isoproterenol > adrenalin >> noradrenaline.Metaproterenol, salbutamolEffect: Bronchodilatation, vasodilation, uterus muscle relaxation, bowel relaxation, stimulation of glycolysis, tremorAdrenergic substance (alpha-1 receptor agonist). Strong and persistent hypertensive action due to peripheral vasoconstriction (increase in blood pressure is about one fifth of epinephrine), pupillary dilation. An agent that stimulates the adrenoreceptor (alpha1) present in the sympathetic nervous system and causes hypertension, and is used to study the effect of a hypotensive drug and the distribution of adrenoreceptors.

Outline

A drug with exciting action on the effector organs of postganglionic sympathetic fibers is referred to as a sympathetic neuron exciting substance or an adrenergic substance. Sympathetic innervation organs have 2 types of receptors, alpha and beta, which are classified into the subtypes alpha-1, alpha-2 and beta-1, beta-2.Alpha-1 receptorAction substance; Adrenalin > noradrenaline > isoproterenol.Phenylephrine, methoxamineEffect: Bronchoconstriction, vasoconstriction, constriction of uterine muscle, bowel relaxation, stimulation of glycolysis, acceleration of lipolysisAlpha-2 receptorAction substance; Noradrenaline = adrenaline > isoproterenol.ClonidineEffect: Inhibition of noradrenaline release from sympathetic nerve ending, inhibition of glycolysis, inhibition of lipolysis, platelet aggregation, inhibition of renin secretionBeta-1 receptorAction substance; Isoproterenol > noradrenaline = adrenaline.DobutamineEffect: Increased heart rate, increased cardiac contractile force, acceleration of lipolysisBeta-2 receptorAction substance; Isoproterenol > adrenalin >> noradrenaline.Metaproterenol, salbutamolEffect: Bronchodilatation, vasodilation, uterus muscle relaxation, bowel relaxation, stimulation of glycolysis, tremorAdrenergic substance (alpha-1 receptor agonist). Strong and persistent hypertensive action due to peripheral vasoconstriction (increase in blood pressure is about one fifth of epinephrine), pupillary dilation.
An agent that stimulates the adrenoreceptor (alpha1) present in the sympathetic nervous system and causes hypertension, and is used to study the effect of a hypotensive drug and the distribution of adrenoreceptors.

Property

Appearance	White, crystals - crystalline powder
pH	pH (10g/L, 25 degrees C) : 4.5 - 5.5
Melting Point	140 - 145 degrees C
Specific Rotation	[α]_D²⁰ -42.0 - -47.5° (c=10, H2O)

Manufacturer Information

Alias

(R)-(-)-PHENYLEPHRINE.HCL
L-PHENYLEPHINE.HCL

Same CAS list

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