Camptothecin
- for Biochemistry
- Specification Assay :
- 98.0+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at 2-10 degrees C.
- CAS RN® :
- 7689-03-4
- Molecular Formula :
- C20H16N2O4
- Molecular Weight :
- 348.35
- GHS :
-
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- Structural Formula
- Label
- Packing
- SDS
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Comparison
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Product Number
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Package Size
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Price
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Availability
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Certificate of Analysis
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Purchase |
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100mg
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In stock in Japan |
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500mg
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In stock in Japan |
※Check availability in the US with the distributor.
Document
Application
Overview / Applications
| Outline | An alkaloid contained in Nothapodytes foetida and Camptotheca acuminata. It has a quinoline skeleton but, biosynthetically, it is a resembling compound of indole alkaloid.This product is a reversible inhibitor of DNA topoisomerase I and it binds to topoisomerase-DNA complex leading to stabilization. It exhibits antileukemic and antitumor activities and inhibits activation of HIV-1 by Tat. It exhibits cytotoxicity to tumorigenetic cells but not to non-tumorigenetic cells. It also induces apoptosis in HL-60 cells and mouse thymus cells.Anticancer irinotecan (Topotecin) is one of its derivatives. |
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Property
| Appearance | Slightly yellow - brown, crystalline powder - powder |
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| Origin / Source | Mappia sp. |
| Specific Rotation | +38 - +48 degrees (D/20 degrees C)(c=0.4,CHCl3-CH3OH) |
Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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