Methotrexate
- for Biochemistry
- Specification Assay :
- 98.0+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at RT.
- CAS RN® :
- 59-05-2
- Molecular Formula :
- C20H22N8O5
- Molecular Weight :
- 454.44
- GHS :
-
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- Structural Formula
- Label
- Packing
- SDS
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Comparison
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Product Number
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Package Size
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Price
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Availability
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Certificate of Analysis
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Purchase |
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1G
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In stock in Japan |
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100mg
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In stock in Japan |
※Check availability in the US with the distributor.
Document
Application
Overview / Applications
| Outline | Aminopterin synthesized in 1947 was found to be effective against leukemia and many types of aminopterin derivatives have been synthesized thereafter. Among them, this product exhibits a more excellent effect and is also effective against malignant chorioepithelioma. It has recently become well known as a therapeutic drug for rheumatism. The pharmacological mechanism inhibits enzyme activity and purine synthesis to inhibit cell proliferation by strongly binding to the enzyme that produces active folic acid necessary for nucleic acid synthesis. |
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Property
| Appearance | Yellow - yellowish brown, crystalline powder - powder |
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| Specific Rotation | +17 - +24 degrees(D/20)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis) |
Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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