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Methotrexate

for Biochemistry
Specification Assay :
98.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at RT.
CAS RN® :
59-05-2
Molecular Formula :
C20H22N8O5
Molecular Weight :
454.44
GHS :
  • Structural Formula
  • Label
  • Packing

If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.

SDS

Basic Information

Comparison
Product Number
Package Size
Price
Inventory
Distributor
135-13573
Barcode No
4987481389854
1g
List Price
448.00 USD

In stock in Japan

Distributor
139-13571
Barcode No
4987481389847
100mg
List Price
85.00 USD

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline Aminopterin synthesized in 1947 was found to be effective against leukemia and many types of aminopterin derivatives have been synthesized thereafter. Among them, this product exhibits a more excellent effect and is also effective against malignant chorioepithelioma. It has recently become well known as a therapeutic drug for rheumatism. The pharmacological mechanism inhibits enzyme activity and purine synthesis to inhibit cell proliferation by strongly binding to the enzyme that produces active folic acid necessary for nucleic acid synthesis.

Property

Appearance Yellow - yellowish brown, crystalline powder - powder
Specific Rotation +17 - +24 degrees(D/20)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)

Manufacturer Information

Alias

Product content may differ from the actual image due to minor specification changes etc.

877-714-1920

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