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Everolimus (mixture of isomers)

for Cellbiology
Specification Assay :
97.0+ % (HPLC)(mixture of isomers)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
159351-69-6
Molecular Formula :
C53H83NO14
Molecular Weight :
958.22
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Availability
Certificate of Analysis
Purchase
Distributor
058-09141
Barcode No
4548995049629
5mg
List Price
139.00 USD

In stock in Japan

Distributor
054-09143
Barcode No
4548995049636
25mg
List Price
570.00 USD

Out of Stock

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.Everolimus is a derivative of rapamycin and an mTOR inhibitor. It is considered to inhibit signal transduction of tumor cells by suppressing activity of mTOR by binding with FK506 binding protein-12 (FKBP-12) and suppress proliferation of the tumor cells, as well as to inhibit angiogenesis by suppressing production of VEGF from tumor cells and growth of vascular endothelial cells by VEGF.
Precautions for Use Packed on argon gas

Property

Appearance white - pale brown, crystalline powder - powder
Solubility Solubility in acetonitrile: to pass test
Specific Rotation -128 - -142 degrees (D/25 degrees C)(c=0.25, CH3CN)

Manufacturer Information

Alias

  • 42-O-(2-Hydroxyethyl)rapamycin

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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