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Detail Information
  1. Top
  2. Analytical Chemistry
  3. Food Analysis
  4. Marine Toxins
  5. Mycalolide B
  1. Top
  2. Life Science
  3. Physiology Research
  4. Toxins
  5. Marine Toxins
  6. Mycalolide B

Mycalolide B

for Biochemistry
Specification Assay :
95.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
122752-21-0
Molecular Formula :
C52H74N4O17
Molecular Weight :
1027.16
GHS :
Citations (1)
PubMed Central® search
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SDS
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Certificate of Analysis
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Distributor
132-12081
Barcode No
4987481298910
100ug
List Price
352.00 USD

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Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.


Recent studies have pinpointed Mycalolide B, a marine toxin, as an inhibitor
of actin polymerization, yet in a manner which differs from that of Cytochalasin
D. Cytochalasin D depolymerized F actin at a slow rate by capping the terminal
binding region of F-actin. Mycalolide B, on the other hand, initiates polymerization
by actually cleaving F-actin with specificity, binding with it at 1:1 (m/m)
ratio and thus restoring it to G-actin.

Mycalolide B has been further attributed with a decrease in Mg2+-ATPase
activity when examining its effects on actomyosin, or various chicken and
rabbit muscular activity.

Solubility: Soluble in methanol, isopropanol and DMSO. IC50:
10-50 nM (L1210 Leukemia cells).

Property

Specific Rotation -53.4℃ (D) (c=1.3 CHCl3)

Manufacturer Information

Alias

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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