Y-27632 ( GMP-compliant )
- for Cell Culture
- Specification Assay :
- 99.5+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep below 25 degrees C.
- CAS RN® :
- 331752-47-7
- Molecular Formula :
- C14H21N3O・2HCl・H2O
- Molecular Weight :
- 338.27
-
Close -
Close
Close
- Structural Formula
- Label
- Packing
|
Comparison
|
Product Number
|
Package Size
|
Price
|
Inventory
|
|
|---|---|---|---|---|---|
|
|
|
5mg
|
|
In stock in Japan |
|
|
|
|
25mg
|
|
In stock in Japan |
Document
Y-27632 Comparison Chart
| ICH-Q7 | ISO9001 | Sterility test |
Viable count test |
Animal- derived- free |
Bacterial Endotoxin test |
Mycoplasma test |
Powder/ Liquid |
References* | |
|---|---|---|---|---|---|---|---|---|---|
| Y-27632 (GMP-compliant)** | ✓ | ✓ | - | ✓ | ✓ | ✓ | ✓ | Powder | - |
| Y-27632, MF*** | - | ✓ | - | ✓ | ✓ | ✓ | ✓ | Powder | |
| CultureSure® Y-27632 | - | ✓ | - | - | ✓ | ✓ | ✓ | Powder | |
| CultureSure® 10mmol/L Y-27632 Solution, Animal-derived-free |
- | ✓ | ✓ | - | ✓ | ✓ | ✓ | Liquid Sterilized with filter |
* Click to move to the PubMed Central® search results.
** This product is complied with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.
*** The manufacturing process and analytical procedure are validated.
Overview / Applications
| Outline | It is a selective and potent inhibitor of ROCK (Rho-associated coiled-coil forming kinase/Rho binding kinase). Y-27632 has a variety of activities including vascular smooth muscle contraction through the ROCK signaling (Ki = 140 nmol/L p160ROCK). This product has been reported to suppress death of human ES/iPS cells at the time of cell dispersion and improves viability of the cells after cryopreservation. This product complies with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products. |
|---|
Property
| Appearance | White - pale yellowish white, crystalline powder or powder |
|---|---|
| Specific Rotation | +2.0 - +10.0 degrees (D/20 degrees C) |
| Purity | Bacterial endotoxins : <0.25EU/mg |
Manufacturer Information
Alias
- ((R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide Dihydrochloride Monohydrate)
For research use or further manufacturing use only. Not for use in diagnostic procedures.
Product content may differ from the actual image due to minor specification changes etc.
If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.