LY 294002
- for Biochemistry
- Specification Assay :
- 97.0+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- CAS RN® :
- 154447-36-6
- Molecular Formula :
- C19H17NO3
- Molecular Weight :
- 307.34
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- Structural Formula
- Label
- Packing
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Comparison
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Product Number
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Package Size
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Price
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Inventory
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5mg
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In stock in Japan |
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10mg
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In stock in Japan |
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25mg
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In stock in Japan |
Document
Application
Overview / Applications
| Outline | LY294002 is a highly cell-permeable, specific phosphatidylinositol 3-kinase (PI3-kinase) inhibitor (IC50 = 1.4 micro M) that acts on the ATP binding site. It does not affect the activity of EGF receptor kinase, MAP kinase, PKC, PI4-kinase, S6 kinase, and c-src at 50 micro M. It inhibits the proliferation of rabbit aorta smooth muscle cells without inducing apoptosis. It is also reported to inhibit histamine secretion by RBL-2H3 cells (IC50 = 5 micro M). |
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Property
| Appearance | White - brown, crystalline powder - powder |
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Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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