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LY 294002

for Biochemistry
Specification Assay :
97.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
154447-36-6
Molecular Formula :
C19H17NO3
Molecular Weight :
307.34
  • Structural Formula
  • Label
  • Packing
Comparison
Product Number
Package Size
Price
Inventory
Distributor
129-04861
Barcode No
4987481397699
5mg
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In stock in Japan

Distributor
125-04863
Barcode No
4987481397705
10mg
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In stock in Japan

Distributor
123-04864
Barcode No
4987481397712
25mg
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Document

Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline LY294002 is a highly cell-permeable, specific phosphatidylinositol 3-kinase (PI3-kinase) inhibitor (IC50 = 1.4 micro M) that acts on the ATP binding site. It does not affect the activity of EGF receptor kinase, MAP kinase, PKC, PI4-kinase, S6 kinase, and c-src at 50 micro M. It inhibits the proliferation of rabbit aorta smooth muscle cells without inducing apoptosis. It is also reported to inhibit histamine secretion by RBL-2H3 cells (IC50 = 5 micro M).

Property

Appearance White - brown, crystalline powder - powder

Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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