Flash Chromatography

Column chromatography is employed in chemical purification process for crude material. Separation of the mixture is done by the difference in interaction between the sample and the stationary / mobile phase after loading the mixture onto the column.
In general, when silica gel with a uniformed particle size is used, the time for adsorption to silica gel becomes longer, so an open column has higher capacity of separation than that of a flash column. Various kinds of silica gel with uniform particle size are available.

Author: Y. Higai


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