Anti Phosphorylated Tau T181, Rat Monoclonal Antibody (2E2-A6)
- for Immunochemistry
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- Source :
- Human
- Cross‒Reactivity :
- Human
- Host :
- Rat
- Clone No. :
- 2E2-A6
- Classification :
- Monoclonal
- Application :
- WB(1:1,000), IHC(1:100 - 1,000)
-
Close
Close
- Structural Formula
- Label
- Packing
|
Comparison
|
Product Number
|
Package Size
|
Price
|
Inventory
|
|
|---|---|---|---|---|---|
|
|
|
10uL
|
|
Discontinued
|
|
|
|
|
50uL
|
|
In stock in Japan |
Document
Product Overview
Tau is a microtubule-associated protein predominantly expressed in the central nervous system and is a major component of the neurofibrillary tangles found in the neurons of patients with Alzheimer's disease. Because the extent of Tau accumulation in the brain correlates with the severity of cognitive impairment, Tau is considered to play a central role in the pathogenesis of Alzheimer's disease. Tau in neurofibrillary tangles is highly phosphorylated, and this phosphorylation is implicated in the pathology of Alzheimer's disease.
“Anti Phosphorylated Tau T181, Rat Monoclonal Antibody (2E2-A6)” is a rat monoclonal antibody that recognizes human Tau phosphorylated threonine 181. It can be used for immunohistochemistry and Western blotting.
Antibody Information
| Clonality | Monoclonal (Clone No. 2E2-A6) |
|---|---|
| Antigen | Synthetic Peptide (171–191 aa of human Tau phosphorylated threonine 181) |
| Host | Rat |
| Formulation | PBS, 50% Glycerol, 0.05% ProClin 300 |
| Conjugate | Unconjugated |
| Cross-reactivity | Human |
| Application | Immunohistochemistry 1:100-1,000 Western blotting 1:1,000 |
Data
Application Data
Immunohistochemistry
- Species:
- Human (Alzheimer’s disease)
- Site:
- Hippocampus CA1
- Sample:
- Paraffin section
Data by courtesy of Dr. Miyasaka, Neuropathology Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University
(affiliation at the time the data were provided)
FAQ
About Antibody
- What is the subclass of this antibody?
- The subclass of this antibody is IgG2b·κ.
- Has this antibody been affinity purified?
- Yes, it has been affinity purified using Protein A.
- What is the concentration of this antibody?
- The specification for protein concentration is 1.0–1.1 mg/mL.
Overview / Applications
| Outline | This product is for research use only. Do not administer it to human.
|
|---|
Property
| Appearance | Liquid |
|---|
Antibody Information
| Antigen | Tau pT181 (aa171-191) |
|---|---|
| Antigen Alias | Tau pT181 (aa171-191) |
| Subclass | IgG2b,k |
| Labeling | Unlabeled |
Manufacturer Information
Alias
- Anti Tau pT181, Rat Monoclonal Antibody (2E2-A6)
For research use or further manufacturing use only. Not for use in diagnostic procedures.
Product content may differ from the actual image due to minor specification changes etc.
If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.