Purification & Characterization
Isolation of compounds obtained by various synthetic methods are carried out through a wide variety of purification methods. Since the purification process occupies more than half of the synthetic (production) process, determination of the purification method is extremely important. Silica gel column chromatography, which is one of the most useful purification methods, is a representative example of a laboratory purification method for obtaining a target product with high purity.
The method makes use of the difference in chemisorption to silica gel when a mixture is being separated and purifed by eluent solvents. In addition, thin layer chromatography (TLC), which traces the reaction process with the same principle, is also an extremely important experimental tool. Since the silica gel column is acidic, a new purification method such as the use of alkaline silica gel for compounds sensitive to acid has been developed.
In addition, in order to reduce the load on the column itself at the time of column purification, a pretreatment column or similar could be used in some cases. There are also other methods such as scavengers that utilizing host-guest chemistry for purification methods.
Cyclodextrin is a compound used in the adsorption purification method. Cyclodextrin removes organic matter in water by inclusion of a hydrophobic compound in it.
Product Line for Purification & Characterization
- Organic Scavengers
- TLC Plates / Silica Gels
- Solid-Phase Extraction Columns