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Icilin

for Cellbiology
Specification Assay :
98.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
36945-98-9
Molecular Formula :
C16H13N3O4
Molecular Weight :
311.29
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Availability
Certificate of Analysis
Purchase
Distributor
096-07181
Barcode No
4548995046192
10mg
List Price
161.00 USD

In stock in Japan

Distributor
092-07183
Barcode No
4548995046208
50mg
Discontinued

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.


Icilin is an agonist of TRPM8 and TRPA1.
TRPM8 is a known cold sensor, which has been considered to become active at below 25-28℃ ; however, a recent study has reported that the reaction temperature is depending on external temperature. TRPM8 is also activated by menthol.
TRPA1 was fist reported as a channel activated by cold stimuli below 17℃. Besides cold stimuli, the channel is also activated by allyl isothiocyanate and cinnamaldehyde, the active components of mustard and cinnamon, respectively, and considered to be involved in pain transduction. The channel has also been reported to be involved in respiratory regulation.

Precautions for Use Packed on inactive gas

Property

Appearance Pale yellow - brown, crystalline powder - powder
Pale yellow - brown, crystalline powder - powder

Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

Product content may differ from the actual image due to minor specification changes etc.

If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.