Dibucaine Hydrochloride

for Biochemistry

Specification Assay :: 98.0+% (After Drying)(Titration)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at RT.

CAS RN^® :: 61-12-1
Molecular Formula :: C20H29N3O2·HCl
Molecular Weight :: 379.92

GHS :

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SDS

Comparison	Product Number	Package Size	Price	Availability	Certificate of Analysis	Purchase
	Distributor 049-20011 Barcode No 4987481252196	1G	List Price 32.00 USD	In stock in Japan	Certificate of Analysis	Distributor
	Distributor 045-20013 Barcode No 4987481252202	5G	List Price 79.00 USD	In stock in Japan	Certificate of Analysis	Distributor

※Check availability in the US with the distributor.

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Same CAS list
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SDS

Product Specification Sheet

Spectral Data

Certificate of Analysis

Calibration Certificate

Application

Overview / Applications

Outline	Nerve cell membranes are charged negatively inside and positively outside in the static state with high extracellular concentrations of Na+ and Cl- and intracellular concentration of K+. However, upon excitation of cells, permeability of Na+ in the cell membrane is increased remarkably and inflow of a large amount of Na+ into cells changes ion distribution generating action potential accompanying depolarization. The excited site where action potential is generated transmits impulses by exciting adjacent static regions in succession. Local anesthetics block excitation conduction in the sensory nerve (anesthetic effect) by lowering Na+ permeability in cell membranes and inhibiting depolarization (stabilization of membrane) necessary for excitation.It inhibits Na+ and K+-ATPase activities. Its local anesthetic effect is more potent and prolonged than cocaine. It is not readily degraded by esterase and has a surface anesthetic effect.>Inhibitory effect on lipophilic protein kinase C.This product is hygroscopic.

Outline

Nerve cell membranes are charged negatively inside and positively outside in the static state with high extracellular concentrations of Na+ and Cl- and intracellular concentration of K+. However, upon excitation of cells, permeability of Na+ in the cell membrane is increased remarkably and inflow of a large amount of Na+ into cells changes ion distribution generating action potential accompanying depolarization. The excited site where action potential is generated transmits impulses by exciting adjacent static regions in succession. Local anesthetics block excitation conduction in the sensory nerve (anesthetic effect) by lowering Na+ permeability in cell membranes and inhibiting depolarization (stabilization of membrane) necessary for excitation.It inhibits Na+ and K+-ATPase activities. Its local anesthetic effect is more potent and prolonged than cocaine. It is not readily degraded by esterase and has a surface anesthetic effect.>

Inhibitory effect on lipophilic protein kinase C.

This product is hygroscopic.

Property

Appearance	White, crystalline powder - powder
pH	pH of a 20g/L solution at 25 degrees C :5.0 - 6.0
Melting Point	99 degrees C

Manufacturer Information

Alias

Same CAS list

Related Information

Product List

Product Name
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Oxethazaine	for Pharmacology Research
Procaine Hydrochloride	for Biochemistry
Tetracaine Hydrochloride	for Biochemistry
D-Tubocurarine Chloride Pentahydrate	Wako 1st Grade
Vecuronium Bromide	for Pharmacology Research
Baclofen	for Biochemistry
Tolperisone Hydrochloride	for Biochemistry

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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