Lipopolysaccharide (LPS) is present in the outer membrane of Gram-negative bacteria. It plays an important role in a number of bioactivities and cell-cell communication. In recent years, LPS is used in vigorous research of natural immunity and self-protection mechanism. our LPS product line will prove useful in induction of different inflammatory responses.
LPS from E. coli is used as an antigen for diagnosis of enterohemorrhagic E. coli infection.
Campylobacter jejuni is a potential etiological factor of Guillain-Barre syndrome, and LPS from Campylobacter jejuni derives from Campylobacter extracted from patients with Guillain-Barre syndrome.
Research has shown that the O-antigen within LPS in Rickettsia and Proteus bacteria share the same structure. LPS from three Proteus bacteria are used as antigens for Weil-Felix test, an agglutination test for the diagnosis of Rickettsia infection (rash, epidemic typhus, and scrub typhus).
P. aeruginosa is relatively resistant to antibiotics and is raising issues as a pathogen of nosocomial infections and opportunistic infections.
Bordetella pertussis is a causative agent of whooping cough which is one of respiratory tract infections. The LPS of Bordetella pertussis, unlike the LPS of E. coli, lacks O-antigens.
We have two types of products prepared by different methods.
[Phenol extraction] Extracted by the Westphal method (using phenol)
[Ultracentrifugation] Those extracted with phenol are purified twice by ultracentrifugation
・E. coli O26、O55、O86a、O103、O111、O113、O127、O128、O150、O157
・Campylobacter jejuni Penner O:19
・Salmonella typhimurium、Salmonella typhimurium G30/C21
・Salmonella minnesota 1114、R595
・Proteus vulgaris OX2、OX19
・Proteus mirabillis OXK
・Pseudomonas aeruginosa PAO1
・Bordetella pertussis Tohama
Desaki, Y. et al.. : Plant Cell Physiol., 47(11), 1530(2006).
Ueda, Y. et al. : Anticancer Res., 26, 4063(2006).
Kamachi, F. et al. : J. Pharmacol. Exp. Ther., 321(1), 345(2007).
Soliman, M. M. et al. : Asian J. Biochem., 4(2), 60(2009).
Kono, K. et al. : Am. J. Physiol. Renal Physiol., 296, F328(2009).
Sritularak, B. et al. : J. Med. Plant. Res., 4(5), 387(2010).
Kobayashi, H. et al. : Microbiol. Res., 167, 48(2011).
Sato, K. et al. : Glycative Stress Research, 1(1), 1(2014).
Miyashita, A. et al. : J. Biol. Chem., 289, 14412(2014).
Shi, M. et al. : Food Chem., 155, 50(2014).
Mori, R. et al. : Am. J. Pathol., 184, 2465(2014).
Nagasaki, T. et al. : Br. J. Cancer, 110, 469(2014).
Shintani, M. et al. : Food Nutr. Sci., 6, 1115(2015).
Kishimoto, M. et al. : Biosci. Microbiota Food Health, 34, 11(2015).
We offer contract production of LPS from Gram-negative bacteria not shown below.
Contact us or sales representative at one of our distributors.
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Escherichia coli (Phenol extraction)
Escherichia coli (Ultracentrifugation)
Campylobacter jejuni (Phenol extraction)
Proteus (Phenol extraction)
Pseudomonas aeruginosa (Ultracentrifugation)
Bordetella pertussis (Ultracentrifugation)
Product content may differ from the actual image due to minor specification changes etc.