Custom Synthesis (Deuterated Compounds)
A custom synthesis service is available for customers seeking deuteration of specific compounds. Utilizing the hydrogen-deuterium exchange developed in-house enables the cost-effective and large-scale supply of a wide range of deuterated compounds. Explore new applications with FUJIFILM Wako -- please feel free to contact us.
Features
- Direct exchange of hydrogen with deuterium in compounds
- Uses deuterium oxide (D2O), the most cost-effective deuterium source
- Scalable from grams to kilograms; large-scale production possible depending on the substrate
What We Offer
- Synthesis of deuterated compounds via H-D exchange reactions
- Subsequent derivatization of deuterated compounds
Applications of Deuterated Compounds
- Pharmacokinetic analysis of drugs
- Trace-level quantitation of pesticide residues in food and endocrine-disrupting substances in the environment
- Higher-order structural analysis of proteins and peptides
- Functional materials such as those used in optical fibers
- Deuterated drugs (also referred to as heavy drugs)
- Organic EL light-emitting materials, etc.
The range of applications for deuterated compounds is expected to continue expanding in the future.
References
- Sajiki, H. et al. : Chem. Pharm. Bull, 66, 21 (2018).
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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