がんを含む様々な疾患研究に
カルナバイオサイエンス社 セリン/スレオニンキナーゼ
カルナバイオサイエンス社は、自社でクローニングしたキナーゼ遺伝子を、昆虫細胞や大腸菌で発現し精製した、高品質のセリン/スレオニンキナーゼタンパク質を提供しています。GSTやHisタグ等アフィニティータグ融合タンパク質に加え、キナーゼのN末端あるいはC末端をビオチン化したビオチン化タンパク質製品もラインアップしています。
大腸菌を用いて作成したキナーゼタンパク質は、キナーゼ活性を検出できないことがあるため、カルナバイオサイエンス社はほとんどのキナーゼ製造に昆虫細胞を利用しています。しかしながら、昆虫細胞由来のキナーゼは、活性は高いものの、精製のために His タグを用いると、精製をした後も、目的以外のキナーゼタンパク質が分離できず残存しやすい特徴があり、それを解決するため、カルナバイオサイエンス社ではタグの第一選択を GST にしています。
2020年11月に経済産業省より「バキュロウイルス生産系を用いて生産された試薬の取扱い見直し」が公表されました。当該見直しのなかで引用された「当該生産系においてはバキュロウイルスが残存しないことを示す学術論」なども踏まえ、カルナバイオサイエンス社のキナーゼタンパク質は、カルタヘナ法規制非該当品として取り扱っております。
特長
高品質
- 精製手法はアフィニティー精製
- 全工程自社製造
- 厳しい規格基準を設定。徹底した品質チェック
高活性
- 文献に基づいて最適化された条件と長年培ったノウハウを用いて製造
高い利便性
- 5ugの少量包装からmg単位のバルクサイズまで幅広い容量を提供可能
- カルタヘナ法規制非該当※
※：経済産業省「バキュロウイルス生産系を用いて生産された試薬の取扱い見直し」に基づく
セリン/スレオニンキナーゼタンパク質製品一覧
※製品情報は、表中の製品名をクリックしてください。
※価格情報は、表中のメーカーコードをクリックしてください。
| プロテインキナーゼ | Tag | ビオチン化 | 製品名 | メーカー コード |
Accession Number | シークエンス | 結合反応 速度例 |
HTRF データ |
|---|---|---|---|---|---|---|---|---|
| ACTR2B(ACVR2B) | N-terminal GST | ACTR2B(ACVR2B) | 09-132 | NP_001097.2 | 161-512(end) | |||
| N-terminal DYKDDDDK | ● | BTN-ACTR2B(ACVR2B) | 09-432-20N | NP_001097.2 | 161-512(end) | |||
| ACVR1C(ALK7) | N-terminal GST | ACVR1C(ALK7) | 09-150 | NP_660302.2 | 139-493(end) | |||
| ACVR2A | N-terminal GST | ACVR2A | 09-131 | NP_001607.1 | 162-513 (end) | |||
| N-terminal DYKDDDDK | ● | BTN-ACVR2A | 09-431-20N | NP_001607.1 | 162-513(end) | ● | ● | |
| ACVRL1(ALK1) | N-terminal GST | ACVRL1(ALK1) | 09-133 | NP_001607.1 | 162-513 | |||
| AKT1 | N-terminal GST | AKT1 | 01-101 | NP_005154.2 | 104-480(end) | |||
| N-terminal DYKDDDDK | ● | BTN-AKT1 | 01-401-20N | NP_005154.2 | 104-480(end) | ● | ● | |
| AKT2 | N-terminal GST | AKT2 | 01-102 | NP_001617.1 | 120-481(end) | |||
| N-terminal DYKDDDDK | ● | BTN-AKT2 | 01-402-20N | NP_001617.1 | 120-481(end) | ● | ||
| AKT3 | N-terminal GST | AKT3 | 01-103 | NP_005456.1 | 108-479(end) | |||
| ALK2(ACVR1) | N-terminal GST | ALK2(ACVR1) | 09-134 | NP_001096.1 | 145-509(end) | |||
| ALK2(ACVR1)[Q207D] | N-terminal GST | ALK2(ACVR1)[Q207D] | 09-149 | NP_001096.1 | 145-509(end) | |||
| ALK2(ACVR1)[R206H] | N-terminal GST | ALK2(ACVR1)[R206H] | 09-148 | NP_001096.1 | 145-509(end) | |||
| ALK4(ACVR1B) | N-terminal GST | ALK4(ACVR1B) | 09-135 | NP_004293.1 | 150-505(end) | |||
| AMPKα1/β1/γ1 | N-terminal GST | AMPKα1/β1/γ1 (PRKAA1/B1/G1) |
02-113 | NP_006242.4 | 1-550(end) | ● | ||
| N-terminal DYKDDDDK | ● | BTN-AMPKα1/β1/γ1 (PRKAA1/B1/G1) |
02-413-20N | NP_006242.4 | 1-550(end) | ● | ● | |
| AMPKα1/β2/γ1 | N-terminal GST | AMPKα1/β2/γ1 (PRKAA1/B2/G1) |
02-147 | NP_006242.4 | 1-550(end) | |||
| N-terminal DYKDDDDK | ● | BTN-AMPKα1/β2/γ1 (PRKAA1/B2/G1) |
02-447-20N | NP_006242.4 | 1-550(end) | ● | ● | |
| AMPKα2/β1/γ1 | N-terminal GST | AMPKα2/β1/γ1 (PRKAA2/B1/G1) |
02-114 | NP_006243.2 | 1-552(end) | |||
| AMPKα2/β2/γ1 | N-terminal GST | AMPKα2/β2/γ1 (PRKAA2/B2/G1) |
02-148 | NP_006243.2 | 1-552(end) | |||
| AurA | N-terminal GST | AurA(AURKA) | 05-101 | NP_940835.1 | 1-403(end) | |||
| N-terminal DYKDDDDK | ● | BTN-AurA(AURKA) | 05-401-20N | NP_940835.1 | 1-403(end) | ● | ● | |
| AurB(AURKB)/INCENP | N-terminal GST | AurB(AURKB) /INCENP |
05-102 | NP_004208.2 | 1-344(end) | |||
| N-terminal DYKDDDDK | ● | BTN-AurB(AURKB) /INCENP※ |
05-402-21N | NP_004208.2 | 1-344(end) | ● | ● | |
| AurC | N-terminal GST | AurC(AURKC) | 05-103 | NP_003151.2 | 1-275(end) | |||
| BARK1(ADRBK1) | N-terminal GST | BARK1(ADRBK1) | 01-111 | NP_001610.2 | 1-689(end) | |||
| N-terminal DYKDDDDK | ● | BTN-BARK1(ADRBK1) | 01-411-20N | NP_001610.2 | 1-689(end) | ● | ||
| BARK2(ADRBK2) | N-terminal GST | BARK2(ADRBK2) | 01-112 | NP_005151.2 | 1-688(end) | |||
| BMPR1A | N-terminal GST | BMPR1A | 09-137 | NP_004320.2 | 187-532 | |||
| BMPR1B | N-terminal GST | BMPR1B(ALK6) | 09-138 | NP_001194.1 | 149-502(end) | |||
| BMPR2 | N-terminal GST | BMPR2 | 09-139 | NP_001195.2 | 174-1038 | |||
| BRAF | N-terminal GST | BRAF | 09-122 | NP_004324.2 | 433-726 | |||
| N-terminal DYKDDDDK | ● | BTN-BRAF | 09-422-20N | NP_004324.2 | 433-726 | ● | ||
| BRAF[T599_V600insT] | N-terminal GST | BRAF[T599_V600insT] | 09-147 | NP_004324.2 | 433-726 | |||
| BRAF[V600E] | N-terminal GST | BRAF[V600E] | 09-144 | NP_004324.2 | 433-726 | |||
| BRSK1 | N-terminal GST | BRSK1 | 02-115 | NP_115806.1 | 1-778(end) | |||
| BRSK2 | N-terminal GST | BRSK2 | 02-116 | ABA17261.1 | 1-674(end) | |||
| BUB1／BUB3 | N-terminal DYKDDDDK | ● | BTN-BUB1／BUB3 | 05-487-20N | NP_004327 | 1-1085(end) | ||
| N-terminal GST | BUB1／BUB3 | 05-187 | NP_004327 | 1-1085(end) | ||||
| BUBR1 | N-terminal GST | BUBR1(BUB1B) | 05-105 | NP_001202.4 | 1-1050(end) | |||
| CaMK1α | N-terminal GST | CaMK1α(CAMK1) | 02-104 | NP_003647.1 | 1-370(end) | |||
| CaMK1β | N-terminal GST | CaMK1β(PNCK) | 02-105 | Q6P2M8 | 1-343(end) | |||
| CaMK1δ | N-terminal GST | CaMK1δ(CAMK1D) | 02-106 | NP_065130.1 | 1-357(end) | |||
| CaMK2α(CAMK2A) | N-terminal GST | CaMK2α(CAMK2A) | 02-109 | NP_741960.1 | 1-478(end) | |||
| CaMK2β(CAMK2B) | N-terminal DYKDDDDK | ● | BTN-CaMK2β(CAMK2B) | 02-410-20N | NP_742078.1(iso5) | 1-503(end) | ● | ● |
| N-terminal GST | CaMK2β(CAMK2B) | 02-110 | NP_742078.1(iso5) | 1-503(end) | ||||
| CaMK2γ(CAMK2G) | N-terminal GST | CaMK2γ(CAMK2G) | 02-112 | NP_751910.1 | 1-518(end) | |||
| CaMK2δ(CAMK2D) | N-terminal DYKDDDDK | ● | BTN-CaMK2δ(CAMK2D) | 02-411-20N | NP_742113.1 | 1-478(end) | ● | ● |
| N-terminal GST | CaMK2δ(CAMK2D) | 02-111 | NP_742113.1 | 1-478(end) | ||||
| CaMK4 | N-terminal GST | CaMK4 | 02-108 | NP_001735.1 | 1-473(end) | |||
| CAMKK1 | N-terminal GST | CAMKK1 | 05-107 | NP_115670.1 | 1-505(end) | |||
| CAMKK2 | N-terminal GST | CAMKK2 | 05-108 | NP_006540.3(isoform-1) | 1-588(end) | |||
| CDC7/ASK | N-terminal GST | CDC7/ASK | 05-109 | NP_003494.1 | 1-574 | |||
| CDK1(CDC2) | N-terminal DYKDDDDK | ● | BTN-CDK1(CDC2) | 04-480-20N | NP_001777.1 | 1-297(end) | ● | |
| CDK1(CDC2)／CycA2 | N-terminal DYKDDDDK | ● | BTN-CDK1(CDC2)／CycA2 | 04-419-20N | NP_001777.1 | 1-297(end) | ● | |
| N-terminal GST | CDK1(CDC2)／CycA2 | 04-119 | NP_001777.1 | 1-297(end) | ||||
| CDK1(CDC2)／CycB1 | N-terminal DYKDDDDK | ● | BTN-CDK1(CDC2)／CycB1 | 04-402-20N | NP_001777.1 | 1-297(end) | ● | |
| N-terminal GST | CDK1(CDC2)／CycB1 | 04-102 | NP_001777.1 | 1-297(end) | ||||
| CDK1(CDC2)／CycE1 | N-terminal GST | CDK1(CDC2)／CycE1 | 04-176 | NP_001777.1 | 1-297(end) | |||
| CDK10(PISSLRE)／CycQ | N-terminal GST | CDK10(PISSLRE)／CycQ | 04-171 | NP_443714.3 | 1-360(end) | |||
| CDK12(CRKRS)(720-1490aa)／CycK | N-terminal DYKDDDDK | ● | BTN-CDK12(CRKRS)(720-1490aa)／CycK | 04-413-20N | NP_057591.2 | 720-1490(end) | ||
| CDK13(CHED)(694-1512aa)／CycK | N-terminal DYKDDDDK | ● | BTN-CDK13(CHED)(694-1512aa)／CycK | 04-482-20N | NP_003709.3 | 694-1512(end) | ||
| CDK13(CHED)／CycK | N-terminal DYKDDDDK | ● | BTN-CDK13(CHED)／CycK | 04-483-20N | NP_003709.3 | 694-1039 | ||
| N-terminal GST, N-terminal His | CDK13(CHED)／CycK | 04-123 | NP_003709.3 | 694-1039 | ||||
| CDK19(CDC2L6)／CycC | N-terminal DYKDDDDK | ● | BTN-CDK19(CDC2L6)／CycC | 04-412-20N | NP_055891.1 | 1-502(end) | ● | ● |
| N-terminal GST | CDK19(CDC2L6)／CycC | 04-112 | NP_055891.1 | 1-502(end) | ||||
| CDK2 | N-terminal DYKDDDDK | ● | BTN-CDK2 | 04-422-20N | NP_001789.2 | 1-298(end) | ||
| CDK2／CycA2 | N-terminal DYKDDDDK | ● | BTN-CDK2／CycA2 | 04-403-20N | NP_001789.2 | 1-298(end) | ● | |
| N-terminal GST | CDK2／CycA2 | 04-103 | NP_001789.2 | 1-298(end) | ||||
| CDK2／CycE1 | N-terminal DYKDDDDK | ● | BTN-CDK2／CycE1 | 04-465-20N | NP_001789.2 | 1-298(end) | ● | |
| N-terminal GST | CDK2／CycE1 | 04-165 | NP_001789.2 | 1-298(end) | ||||
| CDK3 | N-terminal DYKDDDDK | ● | BTN-CDK3 | 04-481-20N | NP_001249.1 | 1-305(end) | ● | |
| CDK3／CycC | N-terminal GST | CDK3／CycC | 04-174 | NP_001249.1 | 1-305(end) | |||
| CDK3／CycE1 | N-terminal DYKDDDDK | ● | BTN-CDK3／CycE1 | 04-404-20N | NP_001249.1 | 1-305(end) | ● | |
| N-terminal GST | CDK3／CycE1 | 04-104 | NP_001249.1 | 1-305(end) | ||||
| CDK4／CycD1 | N-terminal GST | CDK4／CycD1 | 04-120 | NP_000066.1 | 1-303(end) | |||
| CDK4／CycD3 | N-terminal DYKDDDDK | ● | BTN-CDK4／CycD3 | 04-405-20N | NP_000066.1 | 1-303(end) | ● | |
| N-terminal GST | CDK4／CycD3 | 04-105 | NP_000066.1 | 1-303(end) | ||||
| CDK5 | N-terminal DYKDDDDK | ● | BTN-CDK5 | 04-493-20N | NP_004926.1 | 1-292(end) | ● | |
| CDK5／p25 | N-terminal DYKDDDDK | ● | BTN-CDK5／p25 | 04-406-20N | NP_004926.1 | 1-292(end) | ● | |
| N-terminal GST | CDK5／p25 | 04-106 | NP_004926.1 | 1-292(end) | ||||
| CDK5／p35 | N-terminal DYKDDDDK | ● | BTN-CDK5／p35 | 04-492-20N | NP_004926.1 | 1-292(end) | ● | |
| N-terminal GST | CDK5／p35 | 04-192 | NP_004926.1 | 1-292(end) | ||||
| CDK6 | N-terminal DYKDDDDK | ● | BTN-CDK6 | 04-494-20N | NP_001250.1 | 1-326(end) | ● | |
| CDK6／CycD1 | N-terminal GST | CDK6／CycD1 | 04-114 | NP_001250.1 | 1-326(end) | |||
| CDK6／CycD3 | N-terminal DYKDDDDK | ● | BTN-CDK6／CycD3 * | 04-407-20N | NP_001250.1 | 1-326(end) | ● | |
| N-terminal DYKDDDDK | ● | BTN-CDK6／CycD3[non-activated] | 04-407-23N | NP_001250.1 | 1-326(end) | ● | ||
| N-terminal GST | CDK6／CycD3 | 04-107 | NP_001250.1 | 1-326(end) | ||||
| CDK7 | N-terminal DYKDDDDK | ● | BTN-CDK7 | 04-495-20N | NP_001790.1 | 1-346(end) | ||
| CDK7／CycH／MAT1 | N-terminal DYKDDDDK | ● | BTN-CDK7／CycH／MAT1 | 04-408-20N | NP_001790.1 | 1-346(end) | ● | |
| N-terminal GST | CDK7／CycH／MAT1 | 04-108 | NP_001790.1 | 1-346(end) | ||||
| CDK8／CycC | N-terminal DYKDDDDK | ● | BTN-CDK8／CycC | 04-409-20N | NP_001251.1 | 1-464(end) | ● | ● |
| N-terminal GST | CDK8／CycC | 04-109 | NP_001251.1 | 1-464(end) | ||||
| CDK9／CycK | N-terminal DYKDDDDK | ● | BTN-CDK9／CycK | 04-411-20N | NP_001252.1 | 1-372(end) | ● | ● |
| N-terminal GST | CDK9／CycK | 04-111 | NP_001252.1 | 1-372(end) | ||||
| CDK9／CycT1 | N-terminal DYKDDDDK | ● | BTN-CDK9／CycT1 | 04-410-20N | NP_001252.1 | 1-372(end) | ● | |
| N-terminal GST | CDK9／CycT1 | 04-110 | NP_001252.1 | 1-372(end) | ||||
| CDK9／CycT2 | N-terminal DYKDDDDK | ● | BTN-CDK9／CycT2 | 04-421-20N | NP_001252.1 | 1-372(end) | ● | |
| N-terminal GST | CDK9／CycT2 | 04-121 | NP_001252.1 | 1-372(end) | ||||
| CGK2 | N-terminal GST | CGK2(PRKG2) | 01-143 | NP_006250.1 | 1-762 | |||
| CHAK1 | N-terminal GST | CHAK1(TRPM7) | 10-111 | NP_060142.3 | 1158-1865 | |||
| CHK1(CHEK1) | N-terminal DYKDDDDK | ● | BTN-CHK1(CHEK1) | 02-417-20N | NP_001265.2 | 1-476(end) | ● | |
| N-terminal GST | CHK1(CHEK1) | 02-117 | NP_001265.2 | 1-476(end) | ||||
| CHK2(CHEK2) | N-terminal GST | CHK2(CHEK2) | 02-162 | NP_009125.1 | 1-543 | |||
| CK1α | N-terminal GST | CK1α(CSNK1A1) | 03-101 | NP_001883.4 | 1-337 | |||
| CK1γ1 | N-terminal GST | CK1γ1(CSNK1G1) | 03-105 | NP_071331.2 | 1-422 | |||
| CK1γ2 | N-terminal GST | CK1γ2(CSNK1G2) | 03-106 | NP_001310.3 | 1-415 | |||
| CK1γ3 | N-terminal GST | CK1γ3(CSNK1G3) | 03-107 | NP_004375.2 | 1-447 | |||
| CK1δ | N-terminal GST | CK1δ(CSNK1D) | 03-103 | NP_001884.2 | 1-294 | |||
| CK1ε | N-terminal GST | CK1ε(CSNK1E) | 03-104 | NP_001885.1 | 1-348 | |||
| CK2α1/β | N-terminal GST, N-terminal His |
CK2α1/β(CSNK2A1/B) | 05-184 | NP_001886.1(CK2a1), NP_001311.3(Ck2b1) |
1-391(CK2a1), 1-215(CK2b) |
|||
| CK2α2/β | N-terminal GST, N-terminal His |
CK2α2/β(CSNK2A2/B) | 05-185 | NP_0011887.1(CK2a2), NP_001311.3(Ck2b1) |
1-350(CK2a2), 1-215(CK2b) |
|||
| CLK1 | N-terminal GST | CLK1 | 04-126 | NP_004062.2 | 129-484(end) | |||
| CLK2 | N-terminal DYKDDDDK | ● | BTN-CLK2 | 04-427-20N | NP_001281267.1 | 1-499(end) | ● | |
| N-terminal GST | CLK2 | 04-127 | NP_001281267.1 | 1-499(end) | ||||
| CLK3 | N-terminal GST | CLK3 | 04-128 | NP_003983.2 | 1-490(end) | |||
| CLK4 | N-terminal DYKDDDDK | ● | BTN-CLK4 | 04-429-20N | NP_065717.1 | 1-481(end) | ● | |
| N-terminal GST | CLK4 | 04-129 | NP_065717.1 | 1-481(end) | ||||
| COT | - | COT(MAP3K8) | 07-301 | NP_005195.2 | 30-397 | |||
| CRIK | N-terminal GST | CRIK(CIT) | 01-104 | NP_009105.1 | 1-449 | |||
| DAPK1 | N-terminal GST | DAPK1 | 02-134 | NP_004929.1 | 1-289 | |||
| DAPK3 | N-terminal DYKDDDDK | ● | BTN-DAPK3 | 02-436-20N | NP_001339.1 | 1-454(end) | ● | |
| N-terminal GST | DAPK3 | 02-136 | NP_001339.1 | 1-454(end) | ||||
| DCAMKL1 | N-terminal GST | DCAMKL1 | 02-139 | NP_004725.1 | 1-729 | |||
| DCAMKL2 | N-terminal GST | DCAMKL2 | 02-140 | NP_001035350.2 | 1-691 | |||
| DLK | N-terminal DYKDDDDK | ● | BTN-DLK(MAP3K12) | 09-411-20N | NP_006292.3 | 1-520 | ||
| N-terminal GST | DLK(MAP3K12) | 09-111 | NP_006292.3 | 1-520 | ||||
| DMPK1(DMPK) | N-terminal GST | DMPK1(DMPK) | 01-105 | NP_001075032.1 | 1-544 | |||
| DMPK2 | N-terminal GST | DMPK2(CDC42BPG) | 01-106 | NP_059995.2 | 1-473 | |||
| DRAK1 | N-terminal GST | DRAK1(STK17A) | 02-137 | NP_004751.2 | 1-414 | |||
| DYRK1A | N-terminal DYKDDDDK | ● | BTN-DYRK1A | 04-430-20N | NP_001387.2 | 1-763(end) | ● | |
| N-terminal GST | DYRK1A | 04-130 | NP_001387.2 | 1-763(end) | ||||
| DYRK1B | N-terminal GST | DYRK1B | 04-131 | NP_004705.1 | 1-629 | |||
| DYRK2 | N-terminal GST | DYRK2 | 04-132 | NP_003574.1 | 1-528 | |||
| DYRK3 | N-terminal GST | DYRK3 | 04-133 | NP_003573.2 | 1-588 | |||
| DYRK4 | N-terminal DYKDDDDK | DYRK4 | 04-434 | NP_003836.1 | 1-520(end) | |||
| EEF2K | N-terminal GST | EEF2K | 10-113 | NP_037434.1 | 1-725 | |||
| Erk1(MAPK3) | N-terminal GST | Erk1(MAPK3) | 04-142 | NP_002737.1 | 1-379 | |||
| Erk2(MAPK1) | N-terminal GST | Erk2(MAPK1) | 04-143 | NP_002736.3 | 1-360(end) | |||
| Erk5(MAPK7) | N-terminal GST | Erk5(MAPK7) | 04-146 | NP_002740.2 | 1-398 | |||
| Erk7(MAPK15) | N-terminal GST | Erk7(MAPK15) | 04-147 | NP_620590.2 | 1-544(end) | |||
| GCN2(EIF2AK4) | N-terminal DYKDDDDK | ● | BTN-GCN2(EIF2AK4) | 05-453-20N | NP_001013725 | 1-1649(end) | ● | |
| N-terminal GST | GCN2(EIF2AK4) | 05-153 | NP_001013725 | 1-1649(end) | ||||
| GPRK4 | - | GPRK4(GRK4) | 01-313 | NP_892027.2 | 1-578 | |||
| GPRK6 | - | GPRK6(GRK6) | 01-315 | NP_001004105.2 | 1-560 | |||
| GPRK7 | N-terminal GST | GPRK7(GRK7) | 01-116 | NP_631948.1 | 1-553 | |||
| GSK3α | N-terminal GST | GSK3α(GSK3A) | 04-140 | NP_063937.2 | 1-483 | |||
| GSK3β(GSK3B) | N-terminal DYKDDDDK | ● | BTN-GSK3β(GSK3B) | 04-441-20N | NP_001139628.1 | 1-420(end) | ● | ● |
| N-terminal GST | GSK3β(GSK3B) | 04-141 | NP_001139628.1 | 1-420(end) | ||||
| Haspin | N-terminal GST | Haspin(GSG2) | 05-111 | NP_114171.2 | 1-798 | |||
| HGK | N-terminal GST | HGK(MAP4K4) | 07-137 | NP_004825.2 | 1-328 | |||
| HH498 | N-terminal GST | HH498(TNNI3K) | 09-112 | NP_057062.1 | 1-727 | |||
| HIPK1 | N-terminal GST | HIPK1 | 04-135 | NP_689909.2 | 158-555 | |||
| HIPK2 | N-terminal GST | HIPK2 | 04-136 | NP_073577.3 | 1-1198 | |||
| HIPK3 | N-terminal GST | HIPK3 | 04-137 | NP_005725.3 | 161-562 | |||
| HIPK4 | N-terminal GST | HIPK4 | 04-138 | NP_653286.2 | 1-616 | |||
| HPK1(MAP4K1) | N-terminal DYKDDDDK | HPK1(MAP4K1) | 07-410 | NP_009112.1 | 1-346 | |||
| HRI | N-terminal GST | HRI(EIF2AK1) | 05-154 | BAC11461.1 | 1-630(end) | |||
| ICK | N-terminal GST | ICK | 04-156 | NP_057597.2 | 1-632(end) | |||
| IKKα(CHUK) | N-terminal DYKDDDDK | ● | BTN-IKKα(CHUK) | 05-412-20N | NP_001269.3 | 1-745(end) | ● | |
| N-terminal GST | IKKα(CHUK) | 05-112 | NP_001269.3 | 1-745(end) | ||||
| IKKβ | N-terminal DYKDDDDK | ● | BTN-IKKβ(IKBKB) | 05-484-20N | NP_001547.1 | 1-662 | ||
| N-terminal His | IKKβ(IKBKB) | 05-084 | NP_001547.1 | 1-662 | ||||
| IKKε | N-terminal GST | IKKε(IKBKE) | 05-114 | NP_054721.1 | 1-716 | |||
| IRAK1 | N-terminal GST | IRAK1 | 09-101 | NP_001560.2 | 194-712 | |||
| IRAK4 | N-terminal DYKDDDDK | ● | BTN-IRAK4 | 09-445-20N | NP_057207.2 | 1-460(end) | ● | |
| N-terminal GST | IRAK4 | 09-145 | NP_057207.2 | 1-460(end) | ||||
| JNK1(MAPK8) | N-terminal GST | JNK1(MAPK8) | 04-163 | NP_620634.1 | 2-364 | |||
| JNK2(MAPK9) | N-terminal GST | JNK2(MAPK9) | 04-164 | NP_002743.3 | 1-364 | |||
| JNK3 | N-terminal GST | JNK3(MAPK10) | 04-150 | NP_620446.1 | 1-426 | |||
| LATS1／MOBKL1A | N-terminal GST | LATS1／MOBKL1A | 01-523 | NP_004681.1 | 589-1130(end) | |||
| LATS2／MOBKL1A | N-terminal DYKDDDDK | ● | BTN-LATS2／MOBKL1A | 01-424-20N | NP_055387.2 | 553-1088(end) | ● | ● |
| N-terminal GST | LATS2／MOBKL1A | 01-524 | NP_055387.2 | 553-1088(end) | ||||
| LIMK1 | N-terminal GST | LIMK1 | 09-105 | NP_002305.1 | 285-638 | |||
| LIMK2 | N-terminal DYKDDDDK | ● | BTN-LIMK2 | 09-406-20N | NP_005560.1 | 1-638(end) | ● | |
| N-terminal GST | LIMK2 | 09-106 | NP_005560.1 | 1-638(end) | ||||
| LKB1(STK11)/MO25α/STRADα | N-terminal GST | LKB1(STK11)/MO25α /STRADα |
02-119 | NP_000446.1 | 1-433 | |||
| LOK(STK10) | N-terminal GST | LOK(STK10) | 07-115 | NP_005981.3 | 1-968(end) | |||
| LRRK2 | N-terminal GST | LRRK2 | 09-110 | NP_940980.4 | 960-2527(end) | |||
| LRRK2[G2019S] | N-terminal GST | LRRK2[G2019S] | 09-146 | NP_940980.4 | 960-2527(end) | |||
| LZK(MAP3K13) | N-terminal GST | LZK(MAP3K13) | 09-114 | NP_004712.1 | 1-966(end) | |||
| MAP2K1 | N-terminal GST | MAP2K1 | 07-141 | NP_002746.1 | 1-393(end) | |||
| MAP2K1[F129L] | N-terminal GST | MAP2K1[F129L] | 07-151 | NP_002746.1 | 1-393(end) | |||
| MAP2K1[P124L] | N-terminal GST | MAP2K1[P124L] | 07-150 | NP_002746.1 | 1-393(end) | |||
| MAP2K2 | N-terminal GST | MAP2K2 | 07-142 | NP_109587.1 | 1-400 | |||
| MAP2K3 | N-terminal GST | MAP2K3 | 07-143 | NP_659731.1 | 1-347 | |||
| MAP2K4 | N-terminal GST | MAP2K4 | 07-144 | NP_003001.1 | 1-399 | |||
| MAP2K5 | N-terminal GST | MAP2K5 | 07-145 | NP_660143.1 | 1-448 | |||
| MAP2K6 | N-terminal GST | MAP2K6 | 07-146 | NP_002749.2 | 2-334(end) | |||
| MAP2K7 | N-terminal GST | MAP2K7 | 07-148 | NP_660186.1 | 1-419(end) | |||
| MAP3K1 | N-terminal GST | MAP3K1 | 07-103 | NP_005912.1 | 1193-1512(end) | |||
| MAP3K14 | N-terminal GST | MAP3K14 | 07-102 | NP_003945.2 | 319-947(end) | |||
| MAP3K2 | N-terminal GST | MAP3K2 | 07-104 | NP_006600.3 | 336-619 | |||
| MAP3K3 | N-terminal GST | MAP3K3 | 07-105 | NP_002392.2 | 1-626 | |||
| MAP3K4 | N-terminal GST | MAP3K4 | 07-106 | NP_005913.2 | 1312-1608 | |||
| MAP3K5 | N-terminal DYKDDDDK | ● | BTN-MAP3K5 | 07-407-20N | NP_005914.1 | 654-971 | ● | ● |
| N-terminal GST | MAP3K5 | 07-107 | NP_005914.1 | 654-971 | ||||
| MAP3K6 | N-terminal GST | MAP3K6 | 07-108 | NP_004663.3 | 622-950 | |||
| MAP4K2 | N-terminal GST | MAP4K2 | 07-111 | NP_004570.2 | 1-820 | |||
| MAP4K5(KHS1) | N-terminal GST | MAP4K5(KHS1) | 07-113 | NP_006566.2 | 1-846(end) | |||
| MAPKAPK2 | N-terminal GST | MAPKAPK2 | 02-142 | NP_116584.2 | 1-400 | |||
| MAPKAPK3 | N-terminal GST | MAPKAPK3 | 02-143 | NP_004626.1 | 1-382(end) | |||
| MAPKAPK5 | N-terminal GST | MAPKAPK5 | 02-144 | NP_003659.2 | 1-471 | |||
| MARK1 | N-terminal GST | MARK1 | 02-120 | AAF72103.1 | 1-795 | |||
| MARK2 | N-terminal GST | MARK2 | 02-121 | NP_059672.2 | 1-745 | |||
| MARK3 | N-terminal GST | MARK3 | 02-122 | NP_002367.4 | 1-729 | |||
| MARK4 | N-terminal GST | MARK4 | 02-123 | NP_113605.2 | 1-688 | |||
| MELK | N-terminal GST | MELK | 02-124 | NP_055606.1 | 1-493 | |||
| MINK | N-terminal GST | MINK(MINK1) | 07-139 | NP_056531.1 | 1-314 | |||
| MLK1(MAP3K9) | N-terminal DYKDDDDK | ● | BTN-MLK1(MAP3K9) | 09-415-20N | NP_149132.2 | 110-422 | ● | ● |
| N-terminal GST | MLK1(MAP3K9) | 09-115 | NP_149132.2 | 110-422 | ||||
| MLK2(MAP3K10) | N-terminal DYKDDDDK | ● | BTN-MLK2(MAP3K10) | 09-416-20N | NP_002437.2 | 75-462 | ● | ● |
| N-terminal GST | MLK2(MAP3K10) | 09-116 | NP_002437.2 | 75-462 | ||||
| MLK3(MAP3K11) | N-terminal DYKDDDDK | ● | BTN-MLK3(MAP3K11) | 09-417-20N | NP_002410.1 | 99-398 | ● | ● |
| N-terminal GST | MLK3(MAP3K11) | 09-117 | NP_002410.1 | 99-398 | ||||
| MLK4 | N-terminal GST | MLK4 | 09-118 | NP_115811.2 | 114-420 | |||
| MNK1(MKNK1) | N-terminal DYKDDDDK | ● | BTN-MNK1(MKNK1) | 02-445-20N | NP_001129025.1 | 1-424(end) | ||
| N-terminal GST | MNK1(MKNK1) | 02-145 | NP_001129025.1 | 1-424(end) | ||||
| MNK2 | N-terminal GST | MNK2(MKNK2) | 02-146 | NP_951009.1 | 1-465(end) | |||
| MOS | N-terminal GST | MOS | 05-118 | NP_005363.1 | 1-346 | |||
| MRCKα | N-terminal GST | MRCKα(CDC42BPA) | 01-107 | NP_003598.2 | 1-574 | |||
| MRCKβ | N-terminal GST | MRCKβ(CDC42BPB) | 01-108 | NP_006026.3 | 1-473 | |||
| MSK1 | N-terminal GST | MSK1(RPS6KA5) | 01-147 | NP_004746.2 | 1-802 | |||
| MSK2 | N-terminal GST | MSK2(RPS6KA4) | 01-148 | NP_003933.1 | 1-772 | |||
| MSSK1 | N-terminal GST | MSSK1(STK23) | 04-159 | NP_055185.2 | 1-567 | |||
| MST1 | N-terminal GST | MST1(STK4) | 07-116 | NP_006273.1 | 1-487 | |||
| MST2(STK3) | N-terminal DYKDDDDK | ● | BTN-MST2(STK3) | 07-417-20N | NP_006272.2 | 1-491(end) | ● | ● |
| N-terminal GST | MST2(STK3) | 07-117 | NP_006272.2 | 1-491(end) | ||||
| MST3 | N-terminal GST | MST3(STK24) | 07-118 | NP_001027467.2 | 1-431 | |||
| MST4 | N-terminal GST | MST4 | 07-119 | NP_057626.2 | 1-416 | |||
| MYLK4 | N-terminal DYKDDDDK | ● | BTN-MYLK4 | 02-461-20N | NP_001012418.2 | 1-388(end) | ● | |
| N-terminal GST | MYLK4 | 02-161 | NP_001012418.2 | 1-388(end) | ||||
| MYT1 | N-terminal GST | MYT1(PKMYT1) | 05-176 | NP_004194.3 | 1-499 | |||
| NDR1 | N-terminal GST | NDR1(STK38) | 01-125 | NP_009202.1 | 1-465 | |||
| NDR2 | N-terminal GST | NDR2(STK38L) | 01-126 | NP_055815.1 | 1-464 | |||
| NEK1 | N-terminal GST | NEK1 | 05-123 | NP_036356.1 | 1-505 | |||
| NEK11 | N-terminal GST | NEK11 | 05-125 | NP_079076.2 | 1-645 | |||
| NEK2 | - | NEK2 | 05-226 | NP_002488.1 | 1-445 | |||
| NEK3 | N-terminal GST | NEK3 | 05-127 | NP_002489.1 | 1-506 | |||
| NEK4 | N-terminal GST | NEK4 | 05-128 | NP_003148.2 | 1-841 | |||
| NEK6 | N-terminal GST | NEK6 | 05-130 | NP_055212.2 | 1-313 | |||
| NEK7 | N-terminal GST | NEK7 | 05-131 | NP_598001.1 | 1-302 | |||
| NEK9 | N-terminal DYKDDDDK | ● | BTN-NEK9 | 05-433-20N | NP_149107.4 | 1-346, 733-979(end) |
● | |
| N-terminal GST | NEK9 | 05-133 | NP_149107.4 | 1-346, 733-979(end) |
||||
| NIM1K(MGC42105) | N-terminal GST | NIM1K(MGC42105) | 02-175 | NP_699192.1 | 1-436 | |||
| NLK | N-terminal GST | NLK | 04-151 | NP_057315.2 | 121-515 | |||
| NuaK1(ARK5) | N-terminal GST | NuaK1(ARK5) | 02-126 | NP_055655.1 | 1-661 | |||
| NuaK2 | N-terminal DYKDDDDK | ● | BTN-NuaK2 | 02-427-20N | NP_112214.3 | 1-628(end) | ● | ● |
| N-terminal GST | NuaK2 | 02-127 | NP_112214.3 | 1-628(end) | ||||
| OSR1 | N-terminal GST | OSR1(OXSR1) | 07-122 | NP_005100.1 | 1-527 | |||
| p38α(MAPK14) | N-terminal DYKDDDDK | ● | BTN-p38α(MAPK14) | 04-452-20N | NP_620581.1 | 9-352 | ● | |
| N-terminal GST | p38α(MAPK14) | 04-152 | NP_620581.1 | 9-352 | ||||
| p38β | N-terminal GST | p38β(MAPK11) | 04-153 | NP_002742.3 | 1-364 | |||
| p38γ | N-terminal GST | p38γ(MAPK12) | 04-155 | NP_002960.2 | 1-367 | |||
| p38δ | N-terminal GST | p38δ(MAPK13) | 04-154 | NP_002745.1 | 1-365 | |||
| p70S6K(RPS6KB1) | N-terminal GST | p70S6K(RPS6KB1) | 01-156 | NP_003152.1 | 1-421 | |||
| p70S6Kβ(RPS6KB2) | N-terminal GST | p70S6Kβ(RPS6KB2) | 01-155 | NP_003943.2 | 1-482(end) | |||
| PAK1 | N-terminal GST | PAK1 | 07-123 | NP_002567.3 | 1-545 | |||
| PAK2 | N-terminal GST | PAK2 | 07-124 | NP_002568.2 | 1-524 | |||
| PAK3 | N-terminal GST | PAK3 | 07-125 | NP_002569.1 | 1-544 | |||
| PAK4 | N-terminal DYKDDDDK | ● | BTN-PAK4 | 07-426-20N | NP_005875.1 | 1-591(end) | ● | ● |
| N-terminal GST | PAK4 | 07-126 | NP_005875.1 | 1-591(end) | ||||
| PAK5 | N-terminal GST | PAK5(PAK7) | 07-127 | NP_065074.1 | 425-719 | |||
| PAK6 | N-terminal DYKDDDDK | ● | BTN-PAK6 | 07-428-20N | NP_064553.1 | 1-681(end) | ● | ● |
| N-terminal GST | PAK6 | 07-128 | NP_064553.1 | 1-681(end) | ||||
| PASK | N-terminal GST | PASK | 02-128 | NP_055963.2 | 949-1323 | |||
| PBK | N-terminal GST | PBK | 05-168 | NP_060962.2 | 1-322 | |||
| PCTAIRE1(CDK16) ／CycY |
N-terminal GST | PCTAIRE1(CDK16) ／CycY |
04-116 | NP_006192.1 | 107-496(end) | |||
| PDHK1 | N-terminal GST | PDHK1(PDK1) | 10-123 | NP_002601.1 | 1-436 | |||
| PDHK2 | N-terminal GST | PDHK2(PDK2) | 10-140 | NP_002602.2 | 1-407 | |||
| PDHK3 | N-terminal GST | PDHK3(PDK3) | 10-124 | NP_005382.1 | 1-406 | |||
| PDHK4 | N-terminal GST | PDHK4(PDK4) | 10-125 | NP_002603.1 | 1-411 | |||
| PDK1(PDPK1) | N-terminal GST | PDK1(PDPK1) | 01-132 | NP_002604.1 | 1-556(end) | |||
| PEK | N-terminal GST | PEK(EIF2AK3) | 05-155 | NP_004827.3 | 536-1116 | |||
| PGK | N-terminal GST | PGK(PRKG1) | 01-142 | NP_006249.1 | 1-686 | |||
| PHKG1 | N-terminal GST | PHKG1 | 02-152 | NP_006204.1 | 1-387 | |||
| PHKG2 | N-terminal GST | PHKG2 | 02-153 | NP_000285.1 | 1-406 | |||
| PIM1 | N-terminal His | PIM1 | 02-054 | NP_002639.1 | 1-313 | |||
| PIM2 | N-terminal GST | PIM2 | 02-155 | NP_006866.2 | 1-311 | |||
| PIM3 | N-terminal GST | PIM3 | 02-156 | NP_001001852.2 | 1-326(end) | |||
| PKACα(PRKACA) | N-terminal DYKDDDDK | ● | BTN-PKACα(PRKACA) | 01-427-20N | NP_002721.1 | 1-351(end) | ● | ● |
| N-terminal GST | PKACα(PRKACA) | 01-127 | NP_002721.1 | 1-351(end) | ||||
| PKACβ(PRKACB) | N-terminal GST | PKACβ(PRKACB) | 01-128 | NP_002722.1 | 1-351 | |||
| PKACγ | N-terminal GST | PKACγ(PRKACG) | 01-129 | NP_002723.2 | 1-351(end) | |||
| PKCα(PRKCA) | N-terminal DYKDDDDK | ● | BTN-PKCα(PRKCA) | 01-433-20N | NP_002728.1 | 1-672(end) | ● | ● |
| N-terminal GST | PKCα(PRKCA) | 01-133 | NP_002728.1 | 1-672(end) | ||||
| PKCβ1(PRKCB1) | N-terminal GST | PKCβ1(PRKCB1) | 01-134 | NP_997700.1 | 1-671 | |||
| PKCβ2(PRKCB2) | N-terminal GST | PKCβ2(PRKCB2) | 01-165 | NP_002729.2 | 1-673 | |||
| PKCγ(PRKCG) | N-terminal DYKDDDDK | ● | BTN-PKCγ(PRKCG) | 01-437-20N | NP_002730.1 | 1-697(end) | ● | |
| N-terminal GST | PKCγ(PRKCG) | 01-137 | NP_002730.1 | 1-697(end) | ||||
| PKCδ(PRKCD) | N-terminal GST | PKCδ(PRKCD) | 01-135 | NP_006245.2 | 1-676 | |||
| PKCε(PRKCE) | N-terminal GST | PKCε(PRKCE) | 01-136 | NP_005391.1 | 1-737 | |||
| PKCζ | N-terminal GST | PKCζ(PRKCZ) | 01-141 | NP_002735.3 | 1-592 | |||
| PKCη | N-terminal DYKDDDDK | ● | BTN-PKCη(PRKCH) | 01-438-20N | NP_006246 | 1-683(end) | ● | ● |
| N-terminal GST | PKCη(PRKCH) | 01-138 | NP_006246.2 | 1-683(end) | ||||
| PKCθ(PRKCQ) | N-terminal GST | PKCθ(PRKCQ) | 01-140 | NP_006248.1 | 1-706(end) | |||
| PKCι | N-terminal GST | PKCι(PRKCI) | 01-139 | NP_002731.3 | 1-587 | |||
| PKD1 | N-terminal GST | PKD1(PRKD1) | 02-157 | NP_002733.1 | 1-912 | |||
| PKD2 | N-terminal GST | PKD2(PRKD2) | 02-158 | NP_057541.2 | 1-878 | |||
| PKD3 | N-terminal GST | PKD3(PRKD3) | 02-159 | NP_005804.1 | 1-890 | |||
| PKN1 | N-terminal DYKDDDDK | ● | BTN-PKN1 | 01-444-20N | NP_002732.3 | 1-942(end) | ● | ● |
| N-terminal GST | PKN1 | 01-144 | NP_002732.3 | 1-942(end) | ||||
| PKN2 | N-terminal GST | PKN2 | 01-145 | NP_006247.1 | 1-984 | |||
| PKN3 | N-terminal GST | PKN3 | 01-146 | NP_037487.2 | 1-889 | |||
| PKR(EIF2AK2) | N-terminal GST | PKR(EIF2AK2) | 05-156 | NP_002750.1 | 252-551(end) | |||
| PLK1 | N-terminal DYKDDDDK | ● | BTN-PLK1 | 05-457-20N | NP_005021.2 | 1-603(end) | ● | |
| N-terminal GST | PLK1 | 05-157 | NP_005021.2 | 1-603(end) | ||||
| PLK2 | N-terminal GST | PLK2 | 05-158 | NP_006613.2 | 1-685 | |||
| PLK3 | N-terminal GST | PLK3 | 05-159 | NP_004064.2 | 58-340 | |||
| PRKX | N-terminal GST | PRKX | 01-130 | NP_005035.1 | 1-358 | |||
| QIK | N-terminal GST | QIK(SNF1LK2) | 02-129 | NP_056006.1 | 1-926 | |||
| RAF1 | N-terminal DYKDDDDK | ● | BTN-RAF1 | 09-425-20N | NP_002871.1 | 306-648(end) | ● | |
| N-terminal GST | RAF1 | 09-125 | NP_002871.1 | 306-648(end) | ||||
| RIPK2 | N-terminal GST | RIPK2 | 09-128 | NP_003812.1 | 1-305 | |||
| ROCK1 | N-terminal DYKDDDDK | ● | BTN-ROCK1 | 01-409-20N | NP_005397.1 | 1-477 | ● | |
| N-terminal GST | ROCK1 | 01-109 | NP_005397.1 | 1-477 | ||||
| ROCK2 | N-terminal GST | ROCK2 | 01-110 | NP_004841.2 | 1-553 | |||
| RSK1(RPS6KA1) | N-terminal GST | RSK1(RPS6KA1) | 01-149 | NP_002944.2 | 1-735 | |||
| RSK2(RPS6KA3) | N-terminal GST | RSK2(RPS6KA3) | 01-150 | NP_004577.1 | 1-740 | |||
| RSK3(RPS6KA2) | N-terminal GST | RSK3(RPS6KA2) | 01-151 | NP_066958.2 | 1-733 | |||
| RSK4(RPS6KA6) | N-terminal GST | RSK4(RPS6KA6) | 01-152 | NP_055311.1 | 1-745 | |||
| SGK | N-terminal GST | SGK | 01-158 | NP_005618.2 | 61-431 | |||
| SGK2 | N-terminal GST | SGK2 | 01-159 | NP_733794.1 | 1-367 | |||
| SGK3 | N-terminal GST | SGK3(SGKL) | 01-160 | NP_037389.4 | 119-496 | |||
| SIK | N-terminal GST | SIK(SNF1LK) | 02-131 | NP_775490.2 | 1-783(end) | |||
| SIK3(QSK) | N-terminal GST | SIK3(QSK) | 02-130 | NP_001353615.1 | 1-1369aa(end) | |||
| SIK3(QSK)(59-365aa) | N-terminal GST | SIK3(QSK)(59-365aa) | 02-133 | NP_001353615.1 | 59-365aa | |||
| skMLCK | N-terminal GST | skMLCK(MYLK2) | 02-150 | NP_149109.1 | 1-596 | |||
| SLK | N-terminal GST | SLK | 07-129 | NP_055535.1 | 1-1152 | |||
| smMLCK | N-terminal GST | smMLCK(MYLK) | 02-151 | NP_444253.2 | 1428-1771 | |||
| SRPK1 | N-terminal DYKDDDDK | ● | BTN-SRPK1 | 04-460-20N | NP_003128.3 | 1-655(end) | ● | |
| N-terminal GST | SRPK1 | 04-160 | NP_003128.3 | 1-655(end) | ||||
| SRPK2 | N-terminal GST | SRPK2 | 04-161 | NP_872633.1 | 1-688 | |||
| SSTK(TSSK6) | N-terminal GST | SSTK(TSSK6) | 02-163 | NP_114426.1 | 1-273(end) | |||
| STK33 | - | STK33 | 02-301 | NP_112168.1 | 1-514(end) | |||
| STLK3 | N-terminal GST | STLK3(STK39) | 07-130 | NP_037365.2 | 1-545 | |||
| TAK1-TAB1 (MAP3K7) |
C-terminal DYKDDDDK | ● | BTN-TAK1-TAB1 (MAP3K7)※ |
09-419-21C | NP_663304.1 | 1-303 | ● | |
| N-terminal His | TAK1-TAB1(MAP3K7) | 09-019 | NP_663304.1 | 1-303 | ||||
| TAOK2 | N-terminal GST | TAOK2 | 07-133 | NP_004774.1 | 1-319 | |||
| TAOK3 | N-terminal GST | TAOK3 | 07-135 | NP_057365.3 | 1-898(end) | |||
| TBK1 | N-terminal DYKDDDDK | ● | BTN-TBK1 | 05-415-20N | NP_037386.1 | 1-729(end) | ● | ● |
| N-terminal GST | TBK1 | 05-115 | NP_037386.1 | 1-729(end) | ||||
| TESK1 | N-terminal GST | TESK1 | 09-107 | NP_006276.2 | 1-626 | |||
| TGFβR1(TGFBR1) | N-terminal DYKDDDDK | ● | BTN-TGFβR1(TGFBR1)(ALK5) | 09-441-20N | NP_004603.1 | 200-503(end) | ● | |
| N-terminal GST | TGFβR1(TGFBR1) (ALK5) |
09-141 | NP_004603.1 | 200-503(end) | ||||
| TGFβR2 | N-terminal GST | TGFβR2(TGFBR2) | 09-142 | NP_003233.2 | 194-567 | |||
| TLK1 | N-terminal GST | TLK1 | 05-166 | NP_036422.3 | 1-766 | |||
| TLK2 | N-terminal GST | TLK2 | 05-167 | NP_006843.2 | 1-750 | |||
| TNIK | N-terminal DYKDDDDK | ● | BTN-TNIK※ | 07-438-20N | NP_055843.1 | 1-314 | ● | ● |
| N-terminal GST | TNIK | 07-138 | NP_055843.1 | 1-314 | ||||
| TSSK1B(TSSK1) | - | TSSK1B(TSSK1) | 02-364 | NP_114417.1 | 1-367(end) | |||
| TSSK2 | N-terminal GST | TSSK2 | 02-165 | NP_443732.3 | 1-358(end) | |||
| TSSK3 | N-terminal GST | TSSK3 | 02-166 | NP_443073.1 | 2-268(end) | |||
| TTBK1 | N-terminal GST | TTBK1 | 03-108 | NP_115927.1 | 1-343 | |||
| TTBK2 | N-terminal GST | TTBK2 | 03-109 | NP_775771.3 | 1-331 | |||
| TTK | N-terminal GST | TTK | 05-169 | NP_003309.2 | 1-857 | |||
| ULK3 | N-terminal GST | ULK3 | 05-173 | NP_001092906.1 | 1-472(end) | |||
| VRK1 | N-terminal GST | VRK1 | 03-110 | NP_003375.1 | 1-396 | |||
| VRK2 | N-terminal GST | VRK2 | 03-111 | NP_006287.2 | 1-483 | |||
| WEE1 | N-terminal DYKDDDDK | ● | BTN-WEE1 | 05-477-20N | NP_003381.1 | 215-646 | ● | ● |
| N-terminal GST | WEE1 | 05-177 | NP_003381.1 | 215-646 | ||||
| WNK1 | N-terminal DYKDDDDK | ● | BTN-WNK1 | 05-479-20N | NP_061852.1 | 1-491 | ● | |
| N-terminal GST | WNK1 | 05-179 | NP_061852.1 | 1-491 | ||||
| WNK2 | N-terminal GST | WNK2 | 05-180 | NP_006639.3 | 166-489 | |||
| WNK3 | N-terminal GST | WNK3 | 05-181 | NP_065973.2 | 1-434 | |||
| WNK4 | N-terminal DYKDDDDK | ● | BTN-WNK4 | 05-482-20N | NP_115763.2 | 1-444 | ● | |
| N-terminal GST | WNK4 | 05-182 | NP_115763.2 | 1-444 | ||||
| YSK1 | N-terminal GST | YSK1(STK25) | 07-136 | NP_006365.2 | 1-426 | |||
| ZAK | N-terminal GST | ZAK | 09-120 | NP_598407.1 | 1-455 |
※：ATP処理済みビオチン化タンパク質
[non-activated]：ATP未処理のビオチン化タンパク質
セリン/スレオニンキナーゼ基質
inactive：大腸菌で発現させ、通常のキナーゼ製品と比べて非常に低い活性しかもたない、セリン/スレオニンキナーゼです。活性は弱いものの、上流のキナーゼでリン酸化されると活性化され、さらに下流のキナーゼを活性化させる能力を持ちます。
inactive mutant：活性化部位に変異が入っているため、上流のキナーゼでリン酸化はされますが、下流のキナーゼをリン酸化する能力は持ちません。
両方とも基質として使用されます。論理的には、「Inactive mutant 」の方が基質として最適ですが、実際に使用すると、実験系によっては 「inactive」 の方が適している場合もございますので、両製品をお試しいただき、実験系に適した方をご採用ください。
セリン/スレオニンキナーゼ基質タンパク質製品一覧
※製品情報は、表中の製品名をクリックしてください。
※価格情報は、表中のメーカーコードをクリックしてください。
| プロテインキナーゼ | Tag | ビオチン化 | 製品名 | メーカー コード |
Accession Number | シークエンス | 結合反応 速度例 |
|---|---|---|---|---|---|---|---|
| Erk2(MAPK1) [inactive mutant] |
N-terminal GST | Erk2(MAPK1) [inactive mutant] |
04-143-11 | NP_002736.3 | 1-360(end) | ● | |
| Erk2(MAPK1) [inactive] |
N-terminal GST | Erk2(MAPK1) [inactive] |
04-143-10 | NP_002736.3 | 1-360(end) | ● | |
| Erk5(MAPK7) [inactive mutant] |
N-terminal GST | Erk5(MAPK7) [inactive mutant] |
04-145-11 | NP_002740 | 1-398 | ● | |
| Erk5(MAPK7) [inactive] |
N-terminal GST | Erk5(MAPK7) [inactive] |
04-146-10 | NP_002740.2 | 1-398 | ● | |
| IKKα(CHUK) [inactive mutant] |
N-terminal DYKDDDDK | ● | BTN-IKKα(CHUK) [inactive mutant] |
05-412-11-20N | NP_001269.3 | 1-745(end) | ● |
| JNK1(MAPK8) [inactive mutant] |
N-terminal GST | JNK1(MAPK8) [inactive mutant] |
04-163-11 | NP_620634.1 | 2-364 | ● | |
| JNK1(MAPK8) [inactive] |
N-terminal GST | JNK1(MAPK8) [inactive] |
04-163-10 | NP_620634.1 | 2-364 | ● | |
| JNK2(MAPK9) [inactive] |
N-terminal GST | JNK2(MAPK9) [inactive] |
04-164-10 | NP_002743.3 | 1-364 | ||
| MAP2K1 [inactive mutant] |
N-terminal GST | MAP2K1 [inactive mutant] |
07-109-11 | NP_002746.1 | 1-393(end) | ● | |
| MAP2K1 [inactive] |
N-terminal DYKDDDDK | ● | BTN-MAP2K1 [inactive] |
07-441-10-20N | NP_002746.1 | 1-393(end) | ● |
| N-terminal GST | MAP2K1 [inactive] |
07-141-10 | NP_002746.1 | 1-393(end) | ● | ||
| MAP2K6 [inactive mutant] |
N-terminal GST | MAP2K6 [inactive mutant] |
07-146-11 | NP_002749.2 | 1-334(end) | ● | |
| MAP2K6 [inactive] |
N-terminal GST | MAP2K6 [inactive] |
07-146-10 | NP_002749.2 | 1-334(end) | ● | |
| MAP2K7 [inactive mutant] |
N-terminal GST | MAP2K7 [inactive mutant] |
07-110-11 | NP_660186.1 | 1-419(end) | ● | |
| MAP2K7 [inactive] |
N-terminal GST | MAP2K7 [inactive] |
07-147-10 | NP_660186.1 | 1-419(end) | ● | |
| p38α(MAPK14) [inactive mutant] |
N-terminal GST | p38α(MAPK14) [inactive mutant] |
04-152-11 | NP_620581.1 | 9-352 | ● | |
| p38α(MAPK14) [inactive] |
N-terminal DYKDDDDK | ● | BTN-p38α(MAPK14) [inactive] |
04-452-10-20N | NP_620581.1 | 9-352 | ● |
| N-terminal GST | p38α(MAPK14) [inactive] |
04-152-10 | NP_620581.1 | 9-352 | ● |
その他の キナーゼタンパク質 および 基質タンパク質
- 掲載内容は本記事掲載時点の情報です。仕様変更などにより製品内容と実際のイメージが異なる場合があります。
- 掲載されている製品について
- 【試薬】
- 試験・研究の目的のみに使用されるものであり、「医薬品」、「食品」、「家庭用品」などとしては使用できません。
- 試験研究用以外にご使用された場合、いかなる保証も致しかねます。試験研究用以外の用途や原料にご使用希望の場合、弊社営業部門にお問合せください。
- 【医薬品原料】
- 製造専用医薬品及び医薬品添加物などを医薬品等の製造原料として製造業者向けに販売しています。製造専用医薬品(製品名に製造専用の表示があるもの)のご購入には、確認書が必要です。
- 表示している希望納入価格は「本体価格のみ」で消費税等は含まれておりません。
- 表示している希望納入価格は本記事掲載時点の価格です。
Share