UniWells™ Horizontal Co-Culture Plate

• Simultaneous observation using a time-lapse microscope
• No more filter clogging
• Cells are cultured under the same condition (used same material on the bottom)
• Filters of any membrane types and pore sizes are usable
• Both wells are independent (connect in a free combination)

Both cells can be cultured under the same medium volume

• Conventional co-culture plate

  

• UniWells™

  

Filter is prevented from being clogged by cells

• Conventional co-culture plate

  

• UniWells™

  

UniWells™ Horizontal Co-Culture Plate (384-14421)

Main Body A	・・・2
Main Body B	・・・2
Cover	・・・4
Common Cover	・・・4
Adapter	・・・1
O-ring	・・・2
[Note] The filters are sold separately

UniWells™ Horizontal Co-Culture Plate enables the observation that exosomes derived from cell B permeate the filter and are uptaken by cell A.

Comparison of permeability testing of exosome between conventional co-culture plate and UniWells™

1. Cells were seeded to be the same cell numbers into the upper well in conventional co-culture plate and one side well in Uniwells™.
2. Co-culture started after 24 hours from cell seeding.
3. Exosome densities of the cell side and medium side were analyzed.

• Connected use

  Wells are connected by fitting a filter, O-ring and cover.

  ※The filters are sold separately.

  

  Connection methods are as below;

  A)Connect the wells cultured independently by aspirating the culture solution once.
  B)Connect first and increase the volume of the culture solution to achieve co-culture

  

• Single use

  Fit a common cover and cover to a well.

  

  Use in a microscope

  Set wells to the adapter provided.

  ※The adapter is attached to the main unit.