YM-254890

for Cellbiology

Specification Assay :: 95.0+% (HPLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at 2-10 degrees C.

CAS RN^® :: 568580-02-9
Molecular Formula :: C46H69N7O15
Molecular Weight :: 960.08

Citations (22)

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Comparison	Product Number	Package Size	Price	Availability	Certificate of Analysis	Purchase
	Distributor 257-00631 Barcode No 4548995050328	1mg	List Price 363.00 USD	In stock in Japan	Certificate of Analysis	Distributor
	Distributor 253-00633 Barcode No 4548995050335	10mg	Inquire	In stock in Japan	Certificate of Analysis	Distributor

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Overview / Applications

Outline	This product is for research use only. Do not administer it to human. Trimeric G proteins, G_q family specific inhibitor. This is a cyclic depsipeptide isolated from a soil bacterium Chromobacterium sp. QS3666 strain and has a cyclic peptide structure composed of unique amino acids differing from normal amino acids. It specifically inhibits signals mediated by G_q family of trimeric G proteins, G_q, G₁₁ and G₁₄, which are involved in elevated Ca²⁺ level among about 20 types of G proteins, by acting on GDT/GTP exchange reaction. It is a first membrane permeable compound particularly inhibiting G_q signal and a useful tool for a study analyzing G_q signals. Specifically inhibits signals mediated by G_αaq, G_α11, and G_α14 Acts in both in vivo and in vitro systems How to use: dissolve it in DMSO at 1-10 mmol/L to prepare stock solution. In use, accordingly dilute it with an experimental solution. *Go through the stock solution as soon as possible.
Precautions for Use	Packed on argon gas

Outline

This product is for research use only. Do not administer it to human.

Trimeric G proteins, G_q family specific inhibitor.
This is a cyclic depsipeptide isolated from a soil bacterium Chromobacterium sp. QS3666 strain and has a cyclic peptide structure composed of unique amino acids differing from normal amino acids.
It specifically inhibits signals mediated by G_q family of trimeric G proteins, G_q, G₁₁ and G₁₄, which are involved in elevated Ca²⁺ level among about 20 types of G proteins, by acting on GDT/GTP exchange reaction. It is a first membrane permeable compound particularly inhibiting G_q signal and a useful tool for a study analyzing G_q signals.

Specifically inhibits signals mediated by G_αaq, G_α11, and G_α14

Acts in both in vivo and in vitro systems

How to use: dissolve it in DMSO at 1-10 mmol/L to prepare stock solution.
In use, accordingly dilute it with an experimental solution.
*Go through the stock solution as soon as possible.

Precautions for Use

Packed on argon gas

Property

Appearance	White - pale brown, crystalline powder - powder

Manufacturer Information

Alias

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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