Pravastatin Sodium Salt
- for Biochemistry
- Specification Assay :
- 98.0+% (HPLC)
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at 2-10 degrees C.
- CAS RN® :
- 81131-70-6
- Molecular Formula :
- C23H35NaO7
- Molecular Weight :
- 446.51
- GHS :
-
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- Structural Formula
- Label
- Packing
- SDS
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Comparison
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Product Number
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Package Size
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Price
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Inventory
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25mg
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In stock |
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100mg
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In stock in Japan |
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Document
Application
Overview / Applications
| Outline | This product is for research use only. Do not administer it to human.Competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase are the rate limiting enzymes in cholesterol biosynthesis. By blocking the conversion of HMG-CoA to the cholesterol precursor mevalonate, these agents inhibit hepatic synthesis of cholesterol, causing a subsequent stimulation of LDL receptors and an increase in the clearance of LDL and its precursor particles from the circulation. (1) Singer, I. I., et al., Proc. Natl. Acad. Sci. USA, 85, 5264 (1988)(2) Endo, A., et al., FEBS LETTERS, 72, 323 (1976)Lovastatin* is an anti-hypercholesterolemic agent and an inhibitor of 3-hydroxy-3- methylglutaryl coenzyme A (HMG-CoA) reductase.*Note: Not available for sale in the US. Compactin [ML-236B], 95+% (HPLC) (Cat. #033-17301 (25 mg))Lovastatin, 95+% (HPLC) (Cat. #125-04581 (25 mg))Simvastatin, 95+% (HPLC) (Cat. #193-12051 (25 mg), 199-12053 (100 mg)) |
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Property
| Appearance | White - pale yellow, crystals - powder |
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| pH | pH(1g/L, 25 degrees C) : 5.5 - 9.0 |
| Specific Rotation | +144 - +159 degrees (D/20 degrees C)(c=1,H2O) |
Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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