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ISOSPIN Fecal DNA

Manufacturer :
Nippon Gene Co., Ltd.
Storage Condition :
Keep at RT.
GHS :
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Distributor
315-08621
Manufacturer
315-08621
Barcode No
4987481639447
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Package Insert
Spectral Data
Certificate of Analysis
Calibration Certificate
Analytical Charts

Overview

ISOSPIN Fecal DNA

“ISOSPIN Fecal DNA” is DNA extraction and purification kit from fecal sample using spin-column technology. Optimized buffers and physical disruption by beads beating enable to extract DNA from thick cell wall bacteria. Our original spin-column allows purification quickly and easily without phenol and chloroform. This kit requires a Bead homogenizer (available for 2 ml tube) for the bead-beating step.

Features

  • No need to use phenol and chloroform
  • Original spin-column allows for easy operation
  • Estimated time required : 30 min ~ 1 hour
  • Beads beating enable to extract DNA from thick cell wall bacteria
  • Isolate DNA with no RNA by adding RNase A during extraction
  • High yield and quality of DNA from Fecal sample

Simple Protocol​

Simple Protocol

Data

Detection of Bifidobacterium spp. by qPCR

  • Differences in extraction efficiency among DNA extraction kits
    from different companies were compared by qPCR.

    DNA extraction Kit ISOSPIN Fecal DNA , Competitor A and B
    Sample amount 0.2 g of human feces
    Template amount 5 ng of DNA
    qPCR Master Mix DirectAce qPCR Mix plus ROX Tube (318-07751)

     

    Result

    The lowest Ct value was observed when DNA extracted with ISOSPIN Fecal DNA was used as a template.
    This suggests that ISOSPIN Fecal DNA can efficiently extract DNA from Gram-positive bacteria such as Bifidobacterium in human feces.

  • Detection of Bifidobacterium spp. by qPCR

16S rRNA bacterial flora analysis

It performed bacterial flora analysis of DNA extracted from human feces using ISOSPIN Fecal DNA. To confirm reproducibility between fecal collection kit, samples stored with 2 kinds of fecal collection kits were used.

16S rRNA bacterial flora analysis

Result

The DNA extracted with ISOSPIN Fecal DNA was used to perform bacterial flora analysis using a next-generation sequencer. Highly reproducible results were obtained between two kinds of fecal collection kits.

References

ISOSPIN Fecal DNA is used in many papers for purification of bacterial DNA from various samples.

Overview / Applications

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Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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