Highly K+-selective Neutral Ionophore
Valinomycin
Valinomycin, a peptide antibiotic, is a neutral ionophore that acts directly on biomembranes and artificial phospholipid membranes to increase their cation permeability. Due to extremely high K+ selectivity, Valinomycin allows passage of K+ across membranes that are essentially impermeable to the ion and thereby inhibits mitochondrial oxidative phosphorylation by decreasing the membrane potential.
CAS RN®：2001-95-8
C54H90N6O18＝1111.32
- Appearance: White to nearly white crystalline powder to powder
- Solubility in methanol: to pass test
- Assay (HPLC): 93.6% (first production lot)
- Potassium: ≤10 ppm (first production lot)
- Sodium: ≤10 ppm (first production lot)
- Source: Streptomyces tsusimaensis
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For research use or further manufacturing use only. Not for use in diagnostic procedures.
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