Highly K+-selective Neutral Ionophore


Valinomycin, a peptide antibiotic, is a neutral ionophore that acts directly on biomembranes and artificial phospholipid membranes to increase their cation permeability. Due to extremely high K+ selectivity, Valinomycin allows passage of K+ across membranes that are essentially impermeable to the ion and thereby inhibits mitochondrial oxidative phosphorylation by decreasing the membrane potential.

CAS RN®:2001-95-8
  • Appearance: White to nearly white crystalline powder to powder
  • Solubility in methanol: to pass test
  • Assay (HPLC): 93.6% (first production lot)
  • Potassium: ≤10 ppm (first production lot)
  • Sodium: ≤10 ppm (first production lot)
  • Source: Streptomyces tsusimaensis

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For research use or further manufacturing use only. Not for use in diagnostic procedures.

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