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Peptide Synthesis Specialist -PEPTIDE Institute product-

Cellular Delivert Agent-L17E

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An innovative tool, developed by Futaki (Kyoto University), for robust and highlyefficient delivery of biomacromolecules (ex. proteins or antibodies) into the cell. L17E peptide works by preferentially rupturing endosomes to dramatically improve the cytosolic release of endosome-trapped biomacromolecules without cell toxicity.
This compound is manufactured and distributed by Peptide Institute, Inc. under the license of Kyoto University.

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The delivery mechanism of antibody into cells using L17E

Modifications and/or conjugations will also be available via custom services.
For more information, please visit Peptide Institute website.

References

  1. M. Akishiba, T. Takeuchi, Y. Kawaguchi, K. Sakamoto, H. Yu, I. Nakase, T. Nakase, F. Madani, A. Graslund, S. Futaki, Nature Chemistry, 9, 751 (2017). DOI:10.1038/nchem.2779
  2. WO2016/052442 A1

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