FUJIFILM Wako provides unique antibodies for research on cancers, microRNA, autophagy, and fibrosis.
In particular, the anti-asialo GM1 antibody has been used in over 3,000 papers. The glycolipid asialoganglioside GM1 (ASGM1) is expressed in T cells and natural killer (NK) cells upon viral infection. ASGM1 is localized in the lipid raft structure of NK and CD8(+) cells, and the anti-asialo GM1 antibody is said to reduce NK cell activity in various strains of mice and rats.
The anti-asialo GM1 antibody is administered to remove NK cells for functional analysis of NK cells or tumor xenograft in mice.