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Mycalolide B

for Biochemistry
Specification Assay :
95.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at -20 degrees C.
CAS RN® :
122752-21-0
Molecular Formula :
C52H74N4O17
Molecular Weight :
1027.16
  • Structural Formula
  • Label
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Product Number
Package Size
Price
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Distributor
132-12081
Barcode No
4987481298910
100ug
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Document

Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline This product is for research use only. Do not administer it to human.


Recent studies have pinpointed Mycalolide B, a marine toxin, as an inhibitor
of actin polymerization, yet in a manner which differs from that of Cytochalasin
D. Cytochalasin D depolymerized F actin at a slow rate by capping the terminal
binding region of F-actin. Mycalolide B, on the other hand, initiates polymerization
by actually cleaving F-actin with specificity, binding with it at 1:1 (m/m)
ratio and thus restoring it to G-actin.

Mycalolide B has been further attributed with a decrease in Mg2+-ATPase
activity when examining its effects on actomyosin, or various chicken and
rabbit muscular activity.

Solubility: Soluble in methanol, isopropanol and DMSO. IC50:
10-50 nM (L1210 Leukemia cells).

Property

Specific Rotation -53.4℃ (D) (c=1.3 CHCl3)

Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

Product content may differ from the actual image due to minor specification changes etc.

If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.

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