Purification

Liquid chromatography-based nucleic acid separation is widely used for oligonucleotide purification and analysis. Reversed-phase chromatography is based on the principle of separation using differences in hydrophobicity and uses a support of silica gel C18. Anion-exchange chromatography is based on the principle of separation using the polyanionic nature of nucleic acids and uses a support of an anion-exchange resin (rigid polymer, etc.) that is positively charged to capture anions.

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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