Triamcinolone Acetonide

for Biochemistry

Specification Assay :: 98.0+% (HPLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at RT.

CAS RN^® :: 76-25-5
Molecular Formula :: C24H31FO6
Molecular Weight :: 434.50

GHS :

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Comparison	Product Number	Package Size	Price	Inventory
	Distributor 209-10961 Barcode No 4987481343054	1G	List Price JPY 6,800	In stock in Japan	Certificate of Analysis
	Distributor 205-10963 Barcode No 4987481343061	5G	List Price JPY 21,200	In stock in Japan	Certificate of Analysis

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Application

Overview / Applications

Outline	The uppermost surface of the adrenal cortex is covered with connective tissues followed by the zona glomerulosa, zona fasciculata and zona reticularis from outside to inside, and the further inner part is medulla.Mineral corticoid is secreted from the zona glomerulosa, glucocorticoid from the zona fasciculata, and sex hormone (follicular hormone, corpus luteum hormone, androgenic hormone) from the zona reticularis.<:Representative naturally-occurring glucocorticoids include corticosterone and cortisone, and more potent synthetic glucocorticoids with minor adverse effects include prednisolone, triamcinolone and betamethasone.1. Increased blood glucose: Increases blood glucose by inhibiting incorporation and utilization of glucose in the peripheral part.2. Fat metabolism: Has no direct action to decompose fats but enhances lipolysis by other hormones and cyclic AMP.3. Inhibition of vascular hyperpermeability: Constricts peripheral vessels to inhibit vascular hyperpermeability by increasing the sensitivity of smooth muscles to catecholamine.4. Proinflammatory and antiallergic: Inhibits prostaglandin production and reduces inflammation induction and fever. It also inhibits immune response and allergic reaction.Synthetic glucocorticoid. Antiinflammatory and antiallergic action. Stable to acid and persistent action.

Outline

The uppermost surface of the adrenal cortex is covered with connective tissues followed by the zona glomerulosa, zona fasciculata and zona reticularis from outside to inside, and the further inner part is medulla.Mineral corticoid is secreted from the zona glomerulosa, glucocorticoid from the zona fasciculata, and sex hormone (follicular hormone, corpus luteum hormone, androgenic hormone) from the zona reticularis.<:Representative naturally-occurring glucocorticoids include corticosterone and cortisone, and more potent synthetic glucocorticoids with minor adverse effects include prednisolone, triamcinolone and betamethasone.1. Increased blood glucose: Increases blood glucose by inhibiting incorporation and utilization of glucose in the peripheral part.2. Fat metabolism: Has no direct action to decompose fats but enhances lipolysis by other hormones and cyclic AMP.3. Inhibition of vascular hyperpermeability: Constricts peripheral vessels to inhibit vascular hyperpermeability by increasing the sensitivity of smooth muscles to catecholamine.4. Proinflammatory and antiallergic: Inhibits prostaglandin production and reduces inflammation induction and fever. It also inhibits immune response and allergic reaction.Synthetic glucocorticoid. Antiinflammatory and antiallergic action. Stable to acid and persistent action.

Property

Appearance	White - slightly brown, crystalline powder - powder
Melting Point	about 290 degrees C (dec.)
Specific Rotation	[α]_D²⁰ +100 - +107° (c=1, 1,4-dioxane)

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Product List

Product Name
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Betamethasone	for Biochemistry
Betamethasone Dipropionate	for Biochemistry
Betamethasone Valerate	for Biochemistry
Clobetasol Propionate Discontinued	for Biochemistry
Dexamethasone	for Biochemistry
Dexamethasone Sodium Phosphate	for Pharmacology Research
Hydrocortisone	Wako Special Grade
Hydrocortisone Acetate Discontinued	for Pharmacology Research
Prednisolone	for Biochemistry
Adrenocorticotropic Hormone (1-24)(Human)	for Cellbiology
Chlormadinone Acetate Discontinued	for Biochemistry
Danazol Discontinued	for Biochemistry
β-Estradiol	for Biochemistry
Medroxyprogesterone Acetate	for Biochemistry
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