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Prednisolone

for Biochemistry
Specification Assay :
97.0 - 103.0% (molecular absorptiometric analysis)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at RT.
CAS RN® :
50-24-8
Molecular Formula :
C21H28O5
Molecular Weight :
360.44
GHS :
  • Structural Formula
  • Label
  • Packing
SDS
Comparison
Product Number
Package Size
Price
Inventory
Distributor
165-11491
Barcode No
4987481314337
1G
List Price
JPY 6,400

In stock in Japan

Distributor
161-11493
Barcode No
4987481314344
5G
List Price
JPY 20,800

In stock in Japan

Document

SDS
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline The uppermost surface of the adrenal cortex is covered with connective tissues followed by the zona glomerulosa, zona fasciculata and zona reticularis from outside to inside, and the further inner part is medulla.Mineral corticoid is secreted from the zona glomerulosa, glucocorticoid from the zona fasciculata, and sex hormone (follicular hormone, corpus luteum hormone, androgenic hormone) from the zona reticularis.Representative naturally-occurring glucocorticoids include corticosterone and cortisone, and more potent synthetic glucocorticoids with minor adverse effects include prednisolone, triamcinolone and betamethasone.1. Increased blood glucose: Increases blood glucose by inhibiting incorporation/utilization of glucose in the peripheral part.2. Fat metabolism: Has no direct action to decompose fats but enhances lipolysis by other hormones and cyclic AMP.3. Inhibition of vascular hyperpermeability: Constricts peripheral vessels to inhibit vascular hyperpermeability by increasing the sensitivity of smooth muscles to catecholamine.4. Proinflammatory/antiallergic: Inhibits prostaglandin production and reduces inflammation induction and fever. It also inhibits immune response and allergic reaction.Synthetic glucocorticoid. Compared to natural glucocorticoid, it has stronger antiinflammatory action and weaker adverse effects. Its antiinflammatory action is 5 times as strong as cortisone.
A non-naturally occurring synthetic steroid hormone, with adrenocortical hormone action.

Property

Appearance White - nearly white, crystalline powder - powder
Melting Point about 235 degrees C (dec.)
Specific Rotation +97 - +103 degrees (20 degrees C/D)(c=0.5,1,4-dioxane)

Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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