LC/MS Solvents


Designed exclusively for LC/MS analysis and undergo specification testing to ensure suitability, stability and reproducibility including particle test. This minimizes damaging instruments such as pumps and injectors.
By reviewing the manufacturing method, FUJIFILM Wako has achieved a reduction of background noise.



  • Low background noise
  • Uses a special glass bottle that suppresses the elution of sodium, etc. (Japanese Patent No. 4586729)
  • Guarantee particles
  • Conducted "Suitability for LC/MS analysis"

Reduced background noise by reviewing the manufacturing method (ex. Acetonitrile)



  Acetonitrile Methanol 2-Propanol Pure water
QC items specifications
Appearance colorless, clear liquid colorless, clear liquid colorless, clear liquid colorless, clear liquid
Specific Gravity (20°C) 0.780~0.783g/mL 0.789~0.792g/mL 0.784~0.787g/mL 0.997~0.999g/mL
Reflective index (20°C) 1.343~1.346 1.327~1.330 1.376~1.378 1.332~1.334
Absorbance 200nm 0.05 max. - - -
210nm 0.03 max. 0.60 max. 0.05 max. 0.01 max.
220nm 0.02 max. 0.03 max. -
230nm 0.01 max. 0.15 max. 0.10 max.
240nm 0.005 max. 0.06 max. -
254nm - 0.015 max. 0.01 max.
260~400nm - 0.01 max.
Moisture 0.05% max. 0.05% max. 0.05% max. -
Residue after evaporation 0.001% max. 5ppm max. 0.001% max. 5ppm max.
Acidity (as acetic acid) 0.001% max. 0.001% max. 0.001% max. -
Ammonium (as NH4) 0.3ppm max. - - -
peroxide (as H2O2) 5ppm max. 5ppm max. 5ppm max 0.5ppm max
Fluorescence test to pass test to pass test to pass test to pass test
reducing permanganate
to pass test - - to pass test
Gradient test to pass test - - to pass test
Assay (capillary GC) 99.8% min. 99.7% min. 99.7% min. -
pH (25°C) - - - 5.0~7.5
Total organic carbon (TOC) - - - 4ppb max.
Particles (0.5 μm and more) 100/ml max. 100/ml max. 100/ml max. 100/ml max.
Suitability for LC/MS analysis to pass test to pass test to pass test -



Comparison with Competitors

We compared the background data in the QTofMS measurement of our acetonitrile (for LC/MS, Code No. 012-19851, 018-19853) and competitor's equivalent products. While FUJIFILM Wako's product showed a low background, competitor's equivalent products showed a high background after a retention time of 4 min., and impurity peaks were confirmed.
Stable measurement results can be obtained by using FUJIFILM Wako’s LC/MS solvent series.

Positive mode


Negative mode


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Reagents for LC/MS

Adjusted mixture solution of formic acid and acetonitrile for LC/MS use

Author: Y. Higai

For research use or further manufacturing use only. Not for use in diagnostic procedures.

Product content may differ from the actual image due to minor specification changes etc.

If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.

The prices are list prices in Japan.Please contact your local distributor for your retail price in your region.

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