Macrophage Colony-Stimulating Factor ( M-CSF ), Human, recombinant, Animal-derived-free
- for Cell Culture
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- CAS RN® :
- 81627-83-0
- Structural Formula
- Label
- Packing
- SDS
Comparison
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1mg
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10ug
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Out of Stock |
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Document
Overview / Applications
Outline | This product is for research use only. Do not administer it to human. Produced using all non-animal reagents. Colony-stimulating factors were defined as factors that specifically act on monocytic cells and induce colony formation in semisolid medium. M-CSF (Macrophage Colony-Stimulating Factor) acts on the progenitor cells of monocytes and macrophages to promote their differentiation and proliferation. M-CSF prolongs the survival period of mature monocytes and promotes the production of cytokines such as G-CSF, IL-6, IL-8, and TNF-alpha. It also activates the migratory and phagocytic activities of monocytes and macrophages, and enhances SOD production, thereby increasing their cytotoxicity. It also acts on osteoclast progenitor cells, induces RANK expression, and inhibits apoptosis until osteoclast differentiation occurs. M-CSF is associated with a variety of diseases, including abnormal bone formation, carcinogenesis, and atherosclerosis. |
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Precautions for Use | Contents may not be visually confirmed due to trace amounts of contents. Always centrifuge before opening. |
Property
Origin / Source | E. coli expressed human macrophage colony-stimulating factor. |
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Purity | Bacterial endotoxins : <=0.1EU/ug |
Manufacturer Information
Alias
- rhM-CSF
rhM-CSF, Animal-derived-free
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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