α-Mangostin

for Cellbiology

Specification Assay :: 95.0+% (HPLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep below 25 degrees C.

CAS RN^® :: 6147-11-1
Molecular Formula :: C24H26O6
Molecular Weight :: 410.46

Citations (1)

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Comparison	Product Number	Package Size	Price	Availability	Certificate of Analysis	Purchase
	Distributor 132-16241 Barcode No 4987481496804	5mg	List Price 139.00 USD	In stock in Japan	Certificate of Analysis	Distributor

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Overview / Applications

Outline	This product is for research use only. Do not administer it to human. [Anti-Cancer Effect of alpha-Mangostin: Xanthones from Pericarps of Mangosteen] Mangostin, Garcinia mangostana L. is used as a traditional medicine in southeast Asia for inflammatory and septic ailments. The anticancer activity is induced by xanthones such as α-, β-, and γ-mangostin, which are major constituents of the pericarp of mangosteen fruits. α-Mangostin is also reported to induce apoptosis through the activation of intrinsic pathway following the down-regulation of signaling cascades, and also reported to have a cancer preventive effect. References Itoh, T. et al., Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation.: Bioorg. Med. Chem., 16, 4500-8 (2008). Akao, Y. et al., Anti-Cancer Effects of Xanthones from Pericarps of Mangosteen: Int. J. Mol. Sci., 9, 355-70 (2008).

Outline

This product is for research use only. Do not administer it to human.

[Anti-Cancer Effect of alpha-Mangostin: Xanthones from Pericarps of Mangosteen]
Mangostin, Garcinia mangostana L. is used as a traditional medicine in southeast Asia for inflammatory and septic ailments. The anticancer activity is induced by xanthones such as α-, β-, and γ-mangostin, which are major constituents of the pericarp of mangosteen fruits. α-Mangostin is also reported to induce apoptosis through the activation of intrinsic pathway following the down-regulation of signaling cascades, and also reported to have a cancer preventive effect.

References

Itoh, T. et al., Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation.: Bioorg. Med. Chem., 16, 4500-8 (2008).

Akao, Y. et al., Anti-Cancer Effects of Xanthones from Pericarps of Mangosteen: Int. J. Mol. Sci., 9, 355-70 (2008).

Property

Appearance	Pale yellow - yellow, crystalline powder - powder
Origin / Source	Garcinia mangostana
Melting Point	about 181 degrees C

Manufacturer Information

Alias

1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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