Interleukin-1β (IL-1β), Rat, recombinant
- for Cell Culture
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- Structural Formula
- Label
- Packing
- SDS
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1mg
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Out of Stock |
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10ug
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In stock in Japan |
※Check availability in the US with the distributor.
Document
Overview / Applications
| Outline | Interleukin-1beta (IL-1beta) is a pro-inflammatory cytokine produced by various cells such as monocytes, macrophages, keratinocytes, and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and exhibit similar biological properties. The main differences between IL-1alpha and IL-1beta lie in the extent of glycosylation and the fact that IL-1alpha retains sufficient activity in its precursor form, whereas IL-1beta lacks activity in its precursor form. Additionally, IL-1alpha is a cell-bound cytokine, while IL-1beta is a secreted cytokine. IL-1beta activates the MYD88 signaling pathway via the IL-1 receptor type 1. This pathway includes the Toll/IL-1 receptor domain adaptor in the cytoplasm. Carrier protein-free. Sterilized by filtration with a 0.2 um filter, then freeze-dried. |
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| Precautions for Use | This product contains only a small amount of contents, which may not be visible. Be sure to centrifuge before opening the cap. |
Property
| Origin / Source | E. coli expressed rat interleukin-1beta1 |
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| Purity | Bacterial endotoxins : <=0.1EU/ug |
Manufacturer Information
Alias
- rrIL-1β
Catabolin
LAF / Lymphocyte-Activating Factor
EP / Endogenous Pyrogen
LEM / Leukocyte Endogenous Mediator
MCF / Mononuclear Cell Factor
IL-1β, Rat, recombinant
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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