N-Hydroxysuccinimide

for Peptide Synthesis

Specification Assay :: 98.0 - 102.0% (Titration)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at RT.

CAS RN^® :: 6066-82-6
Molecular Formula :: C4H5NO3
Molecular Weight :: 115.09

GHS :

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SDS

Comparison	Product Number	Package Size	Price	Availability	Certificate of Analysis	Purchase
	Distributor 089-04032 Barcode No 4987481275935	25G	List Price 43.00 USD	In stock in Japan	Certificate of Analysis	Distributor
	Distributor 081-04031 Barcode No 4987481275928	100G	List Price 107.00 USD	In stock in Japan	Certificate of Analysis	Distributor

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Spectral Data

Certificate of Analysis

25G
100G

Calibration Certificate

Analytical Charts

Overview / Applications

Outline	This is a reagent that introduces an electron-attracting substituent to the carboxyl group of an amino acid or peptide for activation in order to bind the carboxyl group to the amino group of amine components. Those with an activation substituent introduced to the carboxyl group are called active esters and are generally susceptible to moisture absorption in many cases, but can be isolated and purified and withstand long-term storage in some cases. They are used for increasing the yield of reactants as well as for isolation.The C-teminal of peptide and amino acid can be activated by introducing an electron-attracting substituent to the C-terminal. N-hydroxysuccinimide (HOSu) ester, like pentafluorophenyl (OPfp) ester, has this C-terminal activation action and is called an active ester. This active ester has advantages of mild reaction, generally reacting only with the amino group, not causing transesterification side reaction, and capablity to be isolated.HOSu active ester may be used being isolated but like HOBt, may be often used as an additive for reaction with DCC.

Outline

This is a reagent that introduces an electron-attracting substituent to the carboxyl group of an amino acid or peptide for activation in order to bind the carboxyl group to the amino group of amine components. Those with an activation substituent introduced to the carboxyl group are called active esters and are generally susceptible to moisture absorption in many cases, but can be isolated and purified and withstand long-term storage in some cases. They are used for increasing the yield of reactants as well as for isolation.The C-teminal of peptide and amino acid can be activated by introducing an electron-attracting substituent to the C-terminal. N-hydroxysuccinimide (HOSu) ester, like pentafluorophenyl (OPfp) ester, has this C-terminal activation action and is called an active ester. This active ester has advantages of mild reaction, generally reacting only with the amino group, not causing transesterification side reaction, and capablity to be isolated.HOSu active ester may be used being isolated but like HOBt, may be often used as an additive for reaction with DCC.

Property

Appearance	White, crystals - crystalline powder
Melting Point	about 95 degrees C

Manufacturer Information

Alias

Same CAS list

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