N-Formyl-Met-Leu-Phe
- for Biochemistry
- Manufacturer :
- FUJIFILM Wako Pure Chemical Corporation
- Storage Condition :
- Keep at -20 degrees C.
- CAS RN® :
- 59880-97-6
- Molecular Formula :
- C21H31N3O5S
- Molecular Weight :
- 437.55
- Structural Formula
- Label
- Packing
- SDS
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Certificate of Analysis
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50mg
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In stock in Japan |
※Check availability in the US with the distributor.
Document
Overview / Applications
| Outline | <Pharmacologic and Physiologic Research><Autacoid>Chemotactic peptide. Abbreviated name: fMLP.The most important function of neutrophils is phagocytosis of foreign matters, especially pathogens such as bacteria, and they play an extremely important role in biodefense. As procedures to process the foreign matter, chemostatic ability, phagocytic ability and bactericidal activity function.When bacteria, etc. penetrate into a body, neutrophils go straight to a bacterial focus passing through vascular wall and chemical substances (chemotactic factors) produced by bacteria, and damaged tissues are the factors determining the direction. Chemostatic factors include complement-derived C5a and leukotrienes as well as cell-derived peptides with formylmethionine at the N-terminal.f-MET-Leu-Phe (FMLP), which is a synthetic peptide has been known as a potent chemotactic factor and is used in the measurement of chemotactic ability.<Polypeptide>A synthetic analogue of bacteria-derived peptide chemotactic factor. Monocytes and neutrophils show chemotactic ability at concentrations of 10^-10 to 10^-7 mol/L. |
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Property
| Appearance | White powder |
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| Melting Point | 210 degrees C |
Manufacturer Information
Alias
For research use or further manufacturing use only. Not for use in diagnostic procedures.
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