Compactin

for Biochemistry

Specification Assay :: 95.0+% (HPLC)

Manufacturer :: FUJIFILM Wako Pure Chemical Corporation

Storage Condition :: Keep at 2-10 degrees C.

CAS RN^® :: 73573-88-3
Molecular Formula :: C23H34O5
Molecular Weight :: 390.51

Structural Formula
Label
Packing

SDS

Comparison	Product Number	Package Size	Price	Inventory
	Distributor 033-17301 Barcode No 4987481374348	25mg	List Price 218.00 USD	Out of Stock Inquire	Certificate of Analysis

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Product Specification Sheet

Spectral Data

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25mg

Calibration Certificate

Overview / Applications

Outline	This product is for research use only. Do not administer it to human. Competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase are the rate limiting enzymes in cholesterol biosynthesis. By blocking the conversion of HMG-CoA to the cholesterol precursor mevalonate, these agents inhibit hepatic synthesis of cholesterol, causing a subsequent stimulation of LDL receptors and an increase in the clearance of LDL and its precursor particles from the circulation. (1) Singer, I. I., et al., Proc. Natl. Acad. Sci. USA, 85, 5264 (1988) (2) Endo, A., et al., FEBS LETTERS, 72, 323 (1976) Compactin is the analog of Lovastatin (Wako cat.#125-04581) which is an anti-hypercholesterolemic agent and an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. SOULBILITY: Soluble in methanol, ethanol, acetone, Ethyl acetate, Chloroform, Benzene. Insolble in water, n-hexane. Lovastatin, 95+% (Cat.#125-04581 (25 mg)) Simvastatin, 95+% (HPLC) (Cat.#193-12051 (25 mg), 199-12053 (100 mg)) Pravastatin Sodium, 95+% (HPLC)(Cat.#162-19821 (25 mg), 169-19823 (100 mg))

Outline

This product is for research use only. Do not administer it to human.

Competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase are the rate limiting enzymes in cholesterol biosynthesis. By blocking the conversion of HMG-CoA to the cholesterol precursor mevalonate, these agents inhibit hepatic synthesis of cholesterol, causing a subsequent stimulation of LDL receptors and an increase in the clearance of LDL and its precursor particles from the circulation.

(1) Singer, I. I., et al., Proc. Natl. Acad. Sci. USA, 85, 5264 (1988)
(2) Endo, A., et al., FEBS LETTERS, 72, 323 (1976)
Compactin is the analog of Lovastatin (Wako cat.#125-04581) which is an anti-hypercholesterolemic agent and an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase.
SOULBILITY: Soluble in methanol, ethanol, acetone, Ethyl acetate, Chloroform, Benzene. Insolble in water, n-hexane.

Lovastatin, 95+% (Cat.#125-04581 (25 mg))
Simvastatin, 95+% (HPLC) (Cat.#193-12051 (25 mg), 199-12053 (100 mg))
Pravastatin Sodium, 95+% (HPLC)(Cat.#162-19821 (25 mg), 169-19823 (100 mg))

Property

Appearance	White - nearly white, crystalline powder - powder
Melting Point	152 degrees C

Manufacturer Information

Alias

Same CAS list

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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