Events / Exhibitions
Seminar Life Science Cell Culture
[WEBINAR] Implementing reporter assay-based MAT for rapid pyrogen detection
Join this webinar to discover how reporter assay-based MAT can help laboratories accelerate pyrogen testing, simplify workflows and support the transition to animal-free testing while maintaining confidence in results.
Event Details
- Date & Time
- September 02, 2026, 23:00 pm - 00:00 am JST
- Registration Fee
- Free
- Language
- English
Overview
As the pharmaceutical industry continues to adopt animal-free testing methods, understanding the latest advances in pyrogen detection is becoming increasingly important. This webinar will explore how reporter assay-based MAT can improve assay reproducibility and reduce testing time compared with conventional ELISA-based methods.
This webinar presents primary validation and method suitability test results conducted in accordance with Ph. Eur. 2.6.30, demonstrating its efficacy across multiple pharmaceuticals. Additionally, improved sample throughput and reduced measurement variability enhance assay stability and time efficiency, enabling more practical test designs.
Attendees will gain practical insights into the technology, its implementation and its potential to support more efficient quality control workflows. As you hear about the rabbit pyrogen test (RPT) was removed from the European Pharmacopoeia, increasing demand for MAT and testing methods that enable accurate and highly efficient measurements.Next-generation pyrogen detection kit LumiMAT addresses these issues with a more accurate and simplified testing method. This approach enables accurate and rapid detection (five hours) of various pyrogens and simplifies workflow compared to ELISA-based MAT.
Hear from our expert speaker as you find out how the addition of supplements can improve the NEP spike recovery in previously hard-to-test pharmaceuticals. Validation data will be presented that illustrates use in actual pharmaceutical products, as well as the practical benefits of adding supplements to enhance assay performance and confirming the method's applicability across diverse pharmaceutical formulations.
What you will learn
- Learn about the development of a new MAT method using a luciferase assay as an accurate and rapid alternative to RPT
- Discover the benefits of reporter assay based-MAT, including how it can significantly reduce testing time and simplify operation, leading to decreased variability in results between testers, and how using a cell line instead of PBMCs ensures lot-to-lot variation and stable supply.
- Understand how to perform primary validation and method suitability tests in accordance with Ph. Eur. 2.6.30.
- Explore the case studies: improving NEP spike recovery with supplement addition and high throughput testing using 384-well plates
Whether you are evaluating alternative pyrogen testing methods or looking to improve laboratory efficiency, this webinar will provide practical insights you can apply to your own testing workflows.