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Medroxyprogesterone Acetate

for Biochemistry
Specification Assay :
98.0+% (HPLC)
Manufacturer :
FUJIFILM Wako Pure Chemical Corporation
Storage Condition :
Keep at RT.
CAS RN® :
71-58-9
Molecular Formula :
C24H34O4
Molecular Weight :
386.52
  • Structural Formula
  • Label
  • Packing
SDS
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Product Number
Package Size
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Distributor
138-09991
Barcode No
4987481296244
1G
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In stock in Japan

Distributor
134-09993
Barcode No
4987481296251
5G
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In stock in Japan

Document

SDS ...all
Product Specification Sheet
Spectral Data
Certificate of Analysis
Calibration Certificate

Application

Overview / Applications

Outline <Pharmacological and Physiologic Research><Hormone><Sex Hormone><Female Hormone>Primary follicles mature into Graafian follicles by the action of FSH, and begin to secrete estradiol. This estradiol causes the endometrium to proliferate, while FSH secretion is inhibited (feedback control), resulting in enhanced LH secretion. Graafian follicles are stimulated by LH, and proceed to ovulation and luteinization. LH stimulates the corpus luteum to secrete progesterone, enhances the development of uterine gland tubes and shifts the endometrium to the secretory phase (fully functioning state), while progesterone decreases oxytocin susceptibility of the uterus.Physiological effectFollicular hormone (estradiol); 1. Proliferation of endometrium2. Expression of secondary sexual characteristics3. Increased oxytocin sensitivity of the uterus4. Inhibition of FSH secretion (feedback control)Corpus luteum hormone (progesterone); 1. Changes the endometrium into a secretory phase endometrium (implantation of fertilized egg)2. Hyperthermic action (stimulation of heat center)3. Inhibition of LH secretion4. Reduction of oxytocin susceptibility of the uterus (prevention of miscarriage)Luteinizing hormone agonist having an antitumor activity. Neovascularization inhibitor. Corpus luteum hormone agonist with antitumor activity.
Luteinizing hormone agonist with antitumor activity. It has attracted attention as a neovascularization inhibitor.

Property

Appearance White - slightly brown, crystals - powder
Melting Point about 208 degrees C
Specific Rotation +45 - +51 degrees(D/20 degrees C) (c=1, dioxane)

Manufacturer Information

Alias

For research use or further manufacturing use only. Not for use in diagnostic procedures.

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